Prophylactic endoscopic ligation of high-risk oesophageal varices in a cirrhotic patient with severe haemophilia A

Masahiko Yamada, Yoshihide Fukuda, Yasuo Koyama, Isao Nakano, Fumihiro Urano, Yoshiaki Katano, Kazumi Imada, Hidenori Toyoda, Junki Takamatsu, Masami Imoto, Tetsuo Hayakawa

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

One of the main complications in cirrhosis is haemorrhage from oesophageal varices. It is serious and often fatal, especially in cirrhotic patients with haemophilia. We describe the use of endoscopic variceal ligation (EVL) for prophylaxis of oesophageal variceal bleeding in a high-risk patient, a 40-year-old Japanese man, with severe haemophilia A and liver cirrhosis caused by hepatitis C virus. He had large, coil-shaped varices with a red colour sign, predicting the likelihood of haemorrhage. Administration of omeprazole and factor VIII concentrate achieved rapid healing of the post-EVL ulcers and prevented bleeding from them. Four EVL sessions eradicated oesophageal varices completely, and he has had no recurrence of varices for 2 years, indicating that the procedure was of considerable benefit.

Original languageEnglish
Pages (from-to)151-153
Number of pages3
JournalEuropean Journal of Gastroenterology and Hepatology
Volume10
Issue number2
DOIs
Publication statusPublished - 1998
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

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