TY - JOUR
T1 - Prospective Registry of Embolization of Intracranial Aneurysms Using HydroSoft Coils
T2 - Results of the Japanese HydroSoft Registry
AU - JHSR Collaborators
AU - Imamura, Hirotoshi
AU - Sakai, Nobuyuki
AU - Ito, Yasushi
AU - Sakai, Chiaki
AU - Hyodo, Akio
AU - Miyachi, Shigeru
AU - Matsumaru, Yuji
AU - Yoshimura, Shinichi
AU - Abe, Toshi
AU - Yamagami, Hiroshi
AU - Hayakawa, Mikito
AU - Sato, Hiroaki
AU - Fujinaka, Toshiyuki
AU - Tanabe, Kenichiro
AU - Haraguchi, Koichi
AU - Sakamoto, Makoto
AU - Morimoto, Masashi
AU - Higashi, Toshio
AU - Sugiu, Kenji
AU - Ishii, Akira
AU - Nakahara, Ichiro
AU - Oishi, Hidenori
AU - Matsumoto, Yasushi
AU - Niimi, Yasunari
AU - Yonaha, Hirokatsu
AU - Enomoto, Yukiko
AU - Iinoshi, Tomoshi
AU - Kawanishi, Masahiko
AU - Ushikoshi, Satoshi
AU - Toma, Naoki
AU - Kiura, Sadanori
AU - Mase, Mitshuhito
AU - Izumi, Takashi
N1 - Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/7
Y1 - 2019/7
N2 - Background: The effect of HydroSoft coils on the prevention of recanalization and thrombosis after embolization is unclear. We herein report the results of the single-armed prospective Japanese HydroSoft Registry. Methods: Aneurysms with a diameter of <10 mm that were treated with a ≥50% length of HydroSoft coils were registered. We evaluated the safety and recanalization rate and analyzed the factors related to their recanalization and thrombosis 1 year later. Results: In total, 122 aneurysms were registered. Their mean maximum diameter and neck length were 6.4 and 3.9 mm, respectively. The mean length of the HydroSoft coils was 84.3%. No intracranial hemorrhage occurred, but 2 patients developed minor ischemic strokes. Angiographic examination immediately after the procedure showed complete obliteration, neck remnant (NR), and body filling (BF) in 20 (16.4%), 32 (26.2%), and 67 (54.9%) cases, respectively. One-year follow-up angiography showed complete obliteration, NR, and BF in 68 (55.7%), 15 (12.3%), and 15 (12.3%) cases, respectively, and 5 aneurysms (4.1%) were recanalized (4 and 1 with BF and NR as their initial angiographic result, respectively). Another 11 aneurysms still showed BF, although their thrombosis was promoted. No significant factors related to recanalization were identified. A high volume embolization ratio and small neck were significantly associated with thrombosis 1 year after embolization with HydroSoft coils. Conclusions: The safety and prevention of recanalization 1 year after the treatment appeared acceptable. The high volume embolization ratio associated with HydroSoft coils could induce progression of thrombosis for aneurysms characterized by NR and BF during the follow-up period.
AB - Background: The effect of HydroSoft coils on the prevention of recanalization and thrombosis after embolization is unclear. We herein report the results of the single-armed prospective Japanese HydroSoft Registry. Methods: Aneurysms with a diameter of <10 mm that were treated with a ≥50% length of HydroSoft coils were registered. We evaluated the safety and recanalization rate and analyzed the factors related to their recanalization and thrombosis 1 year later. Results: In total, 122 aneurysms were registered. Their mean maximum diameter and neck length were 6.4 and 3.9 mm, respectively. The mean length of the HydroSoft coils was 84.3%. No intracranial hemorrhage occurred, but 2 patients developed minor ischemic strokes. Angiographic examination immediately after the procedure showed complete obliteration, neck remnant (NR), and body filling (BF) in 20 (16.4%), 32 (26.2%), and 67 (54.9%) cases, respectively. One-year follow-up angiography showed complete obliteration, NR, and BF in 68 (55.7%), 15 (12.3%), and 15 (12.3%) cases, respectively, and 5 aneurysms (4.1%) were recanalized (4 and 1 with BF and NR as their initial angiographic result, respectively). Another 11 aneurysms still showed BF, although their thrombosis was promoted. No significant factors related to recanalization were identified. A high volume embolization ratio and small neck were significantly associated with thrombosis 1 year after embolization with HydroSoft coils. Conclusions: The safety and prevention of recanalization 1 year after the treatment appeared acceptable. The high volume embolization ratio associated with HydroSoft coils could induce progression of thrombosis for aneurysms characterized by NR and BF during the follow-up period.
UR - https://www.scopus.com/pages/publications/85064909805
UR - https://www.scopus.com/inward/citedby.url?scp=85064909805&partnerID=8YFLogxK
U2 - 10.1016/j.wneu.2019.03.234
DO - 10.1016/j.wneu.2019.03.234
M3 - Article
C2 - 30947007
AN - SCOPUS:85064909805
SN - 1878-8750
VL - 127
SP - e631-e637
JO - World Neurosurgery
JF - World Neurosurgery
ER -