The phorbol ester TPA may be intercalated into the membrane phospholipid bilayer and selectively binds to every molecule of C-kinase in exhibiting its full enzymatic activity. Available evidence suggests that C-kinase is the receptive protein of this tumor promoter, and the results presented seem to provide clues for clarifying the mechanism of controlling cell growth and differentiation.
|Number of pages||6|
|Journal||Advances in cyclic nucleotide and protein phosphorylation research|
|Publication status||Published - 01-01-1984|
All Science Journal Classification (ASJC) codes