Pseudoprogression successfully treated with bevacizumab in a child with spinal pilocytic astrocytoma

Kenji Miyata, Toshinori Hori, Yasuto Shimomura, Masahiro Joko, Masakazu Takayasu, Akihisa Okumura

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Clinical case: We report on a 7-year-old female with spinal pilocytic astrocytoma complicated by pseudoprogression 1 month after completion of radiation therapy. Although she was initially treated with high-dose steroids, her clinical symptoms did not completely resolve, and magnetic resonance imaging (MRI) revealed extension of the lesions into the medulla oblongata. Treatment with bevacizumab was commenced, followed by rapid resolution of the clinical symptoms and improvements in the MRI findings. Conclusion: This case highlights the efficacy and tolerability of bevacizumab for the treatment of pseudoprogression in children with spinal low-grade gliomas.

Original languageEnglish
Pages (from-to)2305-2308
Number of pages4
JournalChild's Nervous System
Volume34
Issue number11
DOIs
Publication statusPublished - 01-11-2018
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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