TY - JOUR
T1 - Pulmonary MR angiography with contrast agent at 4 Tesla
T2 - A preliminary result
AU - Uematsu, Hidemasa
AU - Dougherty, Lawrence
AU - Takahashi, Masaya
AU - Ohno, Yoshiharu
AU - Nakatsu, Masashi
AU - Song, Hee Kwon
AU - Ferrari, Victor A.
AU - Gefter, Warren B.
AU - Schnall, Mitchell D.
AU - Hatabu, Hiroto
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2001
Y1 - 2001
N2 - In this study, pulmonary MR angiography (MRA) using a tailored coil at 4 Tesla in conjunction with an intravenous injection of contrast agent is described. Three-dimensional gradient-echo images were obtained during the intravenous injection of 0.05, 0.1, and 0.2 mmol/kg body weight of gadodiamide to investigate the signal enhancement effect of the contrast agent in pulmonary arteries qualitatively and quantitatively. In the qualitative analysis, the subsegmental branches were visualized on every dose. In the quantitative analysis, the average contrast-to-noise ratios (CNRs) of the main pulmonary arteries increased in a dose-dependent manner. However, the CNRs of segmental arteries did not increase as the dose of contrast agent increased, as observed at 1.5 Tesla MRI. These observations demonstrate the feasibility of delineating the pulmonary vasculature using a contrast agent; however, our results also suggest possible high-field-related disabilities that need to be overcome before high-field (≥4 Tesla) MRI can be used to full advantage.
AB - In this study, pulmonary MR angiography (MRA) using a tailored coil at 4 Tesla in conjunction with an intravenous injection of contrast agent is described. Three-dimensional gradient-echo images were obtained during the intravenous injection of 0.05, 0.1, and 0.2 mmol/kg body weight of gadodiamide to investigate the signal enhancement effect of the contrast agent in pulmonary arteries qualitatively and quantitatively. In the qualitative analysis, the subsegmental branches were visualized on every dose. In the quantitative analysis, the average contrast-to-noise ratios (CNRs) of the main pulmonary arteries increased in a dose-dependent manner. However, the CNRs of segmental arteries did not increase as the dose of contrast agent increased, as observed at 1.5 Tesla MRI. These observations demonstrate the feasibility of delineating the pulmonary vasculature using a contrast agent; however, our results also suggest possible high-field-related disabilities that need to be overcome before high-field (≥4 Tesla) MRI can be used to full advantage.
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U2 - 10.1002/mrm.1292
DO - 10.1002/mrm.1292
M3 - Article
C2 - 11675658
AN - SCOPUS:0034759243
SN - 0740-3194
VL - 46
SP - 1028
EP - 1030
JO - Magnetic Resonance in Medicine
JF - Magnetic Resonance in Medicine
IS - 5
ER -