Putaminal magnetic resonance imaging features at various magnetic field strengths in multiple system atrophy

Hirohisa Watanabe, Mizuki Ito, Hiroshi Fukatsu, Jo Senda, Naoki Atsuta, Tomotsugu Kaga, Shigetaka Kato, Masahisa Katsuno, Fumiaki Tanaka, Masaaki Hirayama, Shinji Naganawa, Gen Sobue

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22 Citations (Scopus)

Abstract

We delineated the effects of magnetic field strength on signal intensities to facilitate the specific findings of multiple system atrophy (MSA). Fifteen patients with probable MSA were imaged by 0.35T fast spin-echo (FSE), 1.5T FSE, and 3.0T FSE using a consistent protocol, testing all field strengths on the same day. Sixty patients with probable Parkinson's disease (PD) also underwent imaging. Moderate or marked hyperintensity at the dorsolateral outer putaminal margin, hyperintensity of the putaminal body, hypointensity relative to the globus pallidus at the dorsolateral putaminal margin, and infratentorial signal changes were evaluated as specific findings for MSA. As the field strength increased, the occurrence of hyperintensity both at the dorsolateral outer putaminal margin and of the putaminal body decreased, while the occurrence of hypointensity at the dorsolateral putaminal margin increased in MSA. The occurrence of uniform mild hyperintensity of the outer putaminal margin was evident in 7% at 0.35T, 40% at 1.5T, and 47% at 3.0T in MSA and in 5% at 0.35T, 60% at 1.5T, and 75% at 3.0T in PD. However, no PD patients showed hyperintensity at the dorsolateral outer putaminal margin and that of the putaminal body. Putaminal magnetic resonance imaging (MRI) findings in MSA were altered considerably by magnetic field strength. The severity and distribution of signal changes are important for assessing putaminal MRI findings in MSA.

Original languageEnglish
Pages (from-to)1916-1923
Number of pages8
JournalMovement Disorders
Volume25
Issue number12
DOIs
Publication statusPublished - 15-09-2010
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

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    Watanabe, H., Ito, M., Fukatsu, H., Senda, J., Atsuta, N., Kaga, T., Kato, S., Katsuno, M., Tanaka, F., Hirayama, M., Naganawa, S., & Sobue, G. (2010). Putaminal magnetic resonance imaging features at various magnetic field strengths in multiple system atrophy. Movement Disorders, 25(12), 1916-1923. https://doi.org/10.1002/mds.23196