Quantitative Evaluation of Pain during Electrocutaneous Stimulation using a Log-Linearized Peripheral Arterial Viscoelastic Model

Hiroki Matsubara, Hiroki Hirano, Harutoyo Hirano, Zu Soh, Ryuji Nakamura, Noboru Saeki, Masashi Kawamoto, Masao Yoshizumi, Atsuo Yoshino, Takafumi Sasaoka, Shigeto Yamawaki, Toshio Tsuji

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

In clinical practice, subjective pain evaluations, e.g., the visual analogue scale and the numeric rating scale, are generally employed, but these are limited in terms of their ability to detect inaccurate reports, and are unsuitable for use in anesthetized patients or those with dementia. We focused on the peripheral sympathetic nerve activity that responds to pain, and propose a method for evaluating pain sensation, including intensity, sharpness, and dullness, using the arterial stiffness index. In the experiment, electrocardiogram, blood pressure, and photoplethysmograms were obtained, and an arterial viscoelastic model was applied to estimate arterial stiffness. The relationships among the stiffness index, self-reported pain sensation, and electrocutaneous stimuli were examined and modelled. The relationship between the stiffness index and pain sensation could be modelled using a sigmoid function with high determination coefficients, where R 2 ≥ 0.88, p < 0.01 for intensity, R 2 ≥ 0.89, p < 0.01 for sharpness, and R 2 ≥ 0.84, p < 0.01 for dullness when the stimuli could appropriately evoke dull pain.

Original languageEnglish
Article number3091
JournalScientific reports
Volume8
Issue number1
DOIs
Publication statusPublished - 01-12-2018
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General

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