Quantitative measurement of regional cerebral blood flow with I-123 IMP SPECT: A correction of the microsphere model by global extraction between artery and internal jugular vein

Gen Takeshita; Hiroshi Toyama; Kaori Nakane; Hisato Maeda; Kazuhiro Katada; Akira Takeuchi; Sukehiko Koga

doi:10.1007/BF03164629

Quantitative measurement of regional cerebral blood flow with I-123 IMP SPECT: A correction of the microsphere model by global extraction between artery and internal jugular vein

Gen Takeshita, Hiroshi Toyama, Kaori Nakane, Hisato Maeda, Kazuhiro Katada, Akira Takeuchi, Sukehiko Koga

Radiology

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Quantitative measurements of regional cerebral blood flow with N-isopropyl-(Iodine 123)p-iodoamphetamine (I-123 IMP) as a microsphere model were performed in forty cases. The regional cerebral blood flow values obtained with I-123 IMP were slightly underestimated compared with those of Xe-133 inhalation methods (y=0.90x-2.1, r=0.85, p< 0.01). After correction by global extraction (87 %) between the artery and internal jugular vein, which was measured in four patients by means of a catheter technique, the underestimation of the values obtained with I-123 IMP was improved (y=1.0x-2.4, r=0.85, p< 0.01). Several problems in the accurate quantitative measurement of regional cerebral blood flow with I-123 IMP are discussed.

Original language	English
Pages (from-to)	145-148
Number of pages	4
Journal	Annals of Nuclear Medicine
Volume	5
Issue number	4
DOIs	https://doi.org/10.1007/BF03164629
Publication status	Published - 12-1991

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging

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10.1007/BF03164629

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title = "Quantitative measurement of regional cerebral blood flow with I-123 IMP SPECT: A correction of the microsphere model by global extraction between artery and internal jugular vein",

abstract = "Quantitative measurements of regional cerebral blood flow with N-isopropyl-(Iodine 123)p-iodoamphetamine (I-123 IMP) as a microsphere model were performed in forty cases. The regional cerebral blood flow values obtained with I-123 IMP were slightly underestimated compared with those of Xe-133 inhalation methods (y=0.90x-2.1, r=0.85, p< 0.01). After correction by global extraction (87 %) between the artery and internal jugular vein, which was measured in four patients by means of a catheter technique, the underestimation of the values obtained with I-123 IMP was improved (y=1.0x-2.4, r=0.85, p< 0.01). Several problems in the accurate quantitative measurement of regional cerebral blood flow with I-123 IMP are discussed.",

author = "Gen Takeshita and Hiroshi Toyama and Kaori Nakane and Hisato Maeda and Kazuhiro Katada and Akira Takeuchi and Sukehiko Koga",

year = "1991",

month = dec,

doi = "10.1007/BF03164629",

language = "English",

volume = "5",

pages = "145--148",

journal = "Annals of Nuclear Medicine",

issn = "0914-7187",

publisher = "Springer Japan",

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}

Quantitative measurement of regional cerebral blood flow with I-123 IMP SPECT: A correction of the microsphere model by global extraction between artery and internal jugular vein. / Takeshita, Gen; Toyama, Hiroshi; Nakane, Kaori et al.
In: Annals of Nuclear Medicine, Vol. 5, No. 4, 12.1991, p. 145-148.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Quantitative measurement of regional cerebral blood flow with I-123 IMP SPECT

T2 - A correction of the microsphere model by global extraction between artery and internal jugular vein

AU - Takeshita, Gen

AU - Toyama, Hiroshi

AU - Nakane, Kaori

AU - Maeda, Hisato

AU - Katada, Kazuhiro

AU - Takeuchi, Akira

AU - Koga, Sukehiko

PY - 1991/12

Y1 - 1991/12

N2 - Quantitative measurements of regional cerebral blood flow with N-isopropyl-(Iodine 123)p-iodoamphetamine (I-123 IMP) as a microsphere model were performed in forty cases. The regional cerebral blood flow values obtained with I-123 IMP were slightly underestimated compared with those of Xe-133 inhalation methods (y=0.90x-2.1, r=0.85, p< 0.01). After correction by global extraction (87 %) between the artery and internal jugular vein, which was measured in four patients by means of a catheter technique, the underestimation of the values obtained with I-123 IMP was improved (y=1.0x-2.4, r=0.85, p< 0.01). Several problems in the accurate quantitative measurement of regional cerebral blood flow with I-123 IMP are discussed.

AB - Quantitative measurements of regional cerebral blood flow with N-isopropyl-(Iodine 123)p-iodoamphetamine (I-123 IMP) as a microsphere model were performed in forty cases. The regional cerebral blood flow values obtained with I-123 IMP were slightly underestimated compared with those of Xe-133 inhalation methods (y=0.90x-2.1, r=0.85, p< 0.01). After correction by global extraction (87 %) between the artery and internal jugular vein, which was measured in four patients by means of a catheter technique, the underestimation of the values obtained with I-123 IMP was improved (y=1.0x-2.4, r=0.85, p< 0.01). Several problems in the accurate quantitative measurement of regional cerebral blood flow with I-123 IMP are discussed.

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U2 - 10.1007/BF03164629

DO - 10.1007/BF03164629

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JO - Annals of Nuclear Medicine

JF - Annals of Nuclear Medicine

IS - 4

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Quantitative measurement of regional cerebral blood flow with I-123 IMP SPECT: A correction of the microsphere model by global extraction between artery and internal jugular vein

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