Radiotherapy for persistent malignant transformation from mature cystic teratoma of the ovary

Kosuke Yoshida, Hiroaki Kajiyama, Fumi Utsumi, Hiroko Mitsui, Kiyosumi Shibata, Fumitaka Kikkawa

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Malignant transformations of mature cystic teratomas (MCT) are extremely rare and most of them are squamous cell carcinomas (SCC). Therefore no effective postoperative treatment has been established. In this article, we report two cases in which radiotherapy was effective for SCC arising from MCT. Case 1 was a 64-year-old woman with stage IIA of this tumor. After primary surgery, chemotherapy and interval debulking surgery were performed. She received radiotherapy for relapsed tumors, and has been well for 36 months since the initial diagnosis. Case 2 was a 37-year-old woman with stage IIB of this tumor. After primary debulking surgery, she received chemoradiotherapy for a residual tumor and has been well for 27 months since the surgery. Although there is no established therapy, radiotherapy or concurrent chemoradiotherapy might have beneficial effects on this tumor, similarly to those on SCC from other tissue.

Original languageEnglish
Pages (from-to)584-588
Number of pages5
JournalJournal of Obstetrics and Gynaecology Research
Volume42
Issue number5
DOIs
Publication statusPublished - 01-05-2016

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology

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