Rapid diagnostic testing for antimicrobial stewardship: Utility in Asia Pacific

Anucha Apisarnthanarak, Hong Bin Kim, Luke Moore, Yonghong Xiao, Sanjeev Singh, Yohei Doi, Andrea Lay Hoon Kwa, Sasheela Sri La Sri Ponnampalavanar, Qing Cao, Shin Woo Kim, Hyukmin Lee, Pitak Santanirand

Research output: Contribution to journalReview articlepeer-review

Abstract

Rapid diagnostic testing (RDT) can provide prompt, accurate identification of infectious organisms and be a key component of antimicrobial stewardship (AMS) programs. However, their use is less widespread in Asia Pacific than western countries. Cost can be prohibitive, particularly in less resource-replete settings. A selective approach is required, possibly focusing on the initiation of antimicrobials, for differentiating bacterial versus viral infections and identifying locally relevant tropical diseases. Across Asia Pacific, more data are needed on RDT use within AMS, focusing on the impact on antimicrobial usage, patient morbidity and mortality, and cost effectiveness. Moreover, in the absence of formal guidelines, regional consensus statements to guide clinical practice are warranted. These will provide a regionally relevant definition for RDT; greater consensus on its role in managing infections; advice on implementation and overcoming barriers; and guidance on optimizing human resource capacity. By addressing these issues, the outcomes of AMS programs should improve.

Original languageEnglish
JournalInfection Control and Hospital Epidemiology
DOIs
Publication statusAccepted/In press - 2021

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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