TY - JOUR
T1 - Rapid diagnostic testing for antimicrobial stewardship
T2 - Utility in Asia Pacific
AU - Apisarnthanarak, Anucha
AU - Kim, Hong Bin
AU - Moore, Luke
AU - Xiao, Yonghong
AU - Singh, Sanjeev
AU - Doi, Yohei
AU - Kwa, Andrea Lay Hoon
AU - Sri La Sri Ponnampalavanar, Sasheela
AU - Cao, Qing
AU - Kim, Shin Woo
AU - Lee, Hyukmin
AU - Santanirand, Pitak
N1 - Publisher Copyright:
© 2021 Cambridge University Press. All rights reserved.
PY - 2021/7
Y1 - 2021/7
N2 - Rapid diagnostic testing (RDT) can provide prompt, accurate identification of infectious organisms and be a key component of antimicrobial stewardship (AMS) programs. However, their use is less widespread in Asia Pacific than western countries. Cost can be prohibitive, particularly in less resource-replete settings. A selective approach is required, possibly focusing on the initiation of antimicrobials, for differentiating bacterial versus viral infections and identifying locally relevant tropical diseases. Across Asia Pacific, more data are needed on RDT use within AMS, focusing on the impact on antimicrobial usage, patient morbidity and mortality, and cost effectiveness. Moreover, in the absence of formal guidelines, regional consensus statements to guide clinical practice are warranted. These will provide a regionally relevant definition for RDT; greater consensus on its role in managing infections; advice on implementation and overcoming barriers; and guidance on optimizing human resource capacity. By addressing these issues, the outcomes of AMS programs should improve.
AB - Rapid diagnostic testing (RDT) can provide prompt, accurate identification of infectious organisms and be a key component of antimicrobial stewardship (AMS) programs. However, their use is less widespread in Asia Pacific than western countries. Cost can be prohibitive, particularly in less resource-replete settings. A selective approach is required, possibly focusing on the initiation of antimicrobials, for differentiating bacterial versus viral infections and identifying locally relevant tropical diseases. Across Asia Pacific, more data are needed on RDT use within AMS, focusing on the impact on antimicrobial usage, patient morbidity and mortality, and cost effectiveness. Moreover, in the absence of formal guidelines, regional consensus statements to guide clinical practice are warranted. These will provide a regionally relevant definition for RDT; greater consensus on its role in managing infections; advice on implementation and overcoming barriers; and guidance on optimizing human resource capacity. By addressing these issues, the outcomes of AMS programs should improve.
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U2 - 10.1017/ice.2021.149
DO - 10.1017/ice.2021.149
M3 - Review article
C2 - 34128462
AN - SCOPUS:85108105565
SN - 0899-823X
VL - 42
SP - 864
EP - 868
JO - Infection Control and Hospital Epidemiology
JF - Infection Control and Hospital Epidemiology
IS - 7
ER -