TY - JOUR
T1 - Rare complication characterized by late-onset transient neurological symptoms without hyperperfusion after carotid artery stenting
T2 - A report of three cases
AU - Fukushima, Yutaka
AU - Nakahara, Ichiro
AU - Ohta, Tsuyoshi
AU - Matsumoto, Shoji
AU - Ishibashi, Ryota
AU - Gomi, Masanori
AU - Miyata, Haruka
AU - Nishi, Hidehisa
AU - Watanabe, Sadayoshi
N1 - Publisher Copyright:
© The Author(s) 2015.
PY - 2015/2/1
Y1 - 2015/2/1
N2 - We experienced a rare complication after carotid artery stenting (CAS) characterized by transient neurological symptoms with no evidence of distal emboli or hyperperfusion. Using neuroimaging, we investigated the pathogenesis of the complication that occurred after CAS in three patients who developed neurological symptoms over a period of ten hours after CAS and improved within two days. None of the three patients showed signs of fresh infarctions on diffusion-weighted imaging or hyperperfusion on single-photon emission computed tomography. However, high signal intensity was observed in the leptomeningeal zone of the cerebral hemisphere on the stent side in all three patients and in the leptomeningeal zone of the contralateral anterior cerebral artery territory in one patient. These areas were assessed using fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging without gadolinium administration. The high signal intensity in the leptomeningeal zone disappeared as the symptoms improved. Based on the transient nature of the neurological disorders and the normalization of FLAIR imaging findings in these patients, the pathogenesis of this complication might have been vasogenic edema due to vasoparalysis of the local vessels caused by the hemodynamic changes occurring after CAS.
AB - We experienced a rare complication after carotid artery stenting (CAS) characterized by transient neurological symptoms with no evidence of distal emboli or hyperperfusion. Using neuroimaging, we investigated the pathogenesis of the complication that occurred after CAS in three patients who developed neurological symptoms over a period of ten hours after CAS and improved within two days. None of the three patients showed signs of fresh infarctions on diffusion-weighted imaging or hyperperfusion on single-photon emission computed tomography. However, high signal intensity was observed in the leptomeningeal zone of the cerebral hemisphere on the stent side in all three patients and in the leptomeningeal zone of the contralateral anterior cerebral artery territory in one patient. These areas were assessed using fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging without gadolinium administration. The high signal intensity in the leptomeningeal zone disappeared as the symptoms improved. Based on the transient nature of the neurological disorders and the normalization of FLAIR imaging findings in these patients, the pathogenesis of this complication might have been vasogenic edema due to vasoparalysis of the local vessels caused by the hemodynamic changes occurring after CAS.
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U2 - 10.15274/INR-2014-10099
DO - 10.15274/INR-2014-10099
M3 - Article
C2 - 25934779
AN - SCOPUS:84930061112
SN - 1591-0199
VL - 21
SP - 72
EP - 79
JO - Interventional Neuroradiology
JF - Interventional Neuroradiology
IS - 1
ER -