Reactivation of herpesvirus type 6 in children receiving bone marrow transplants for leukemia

Yoshizo Asano, Tetsushi Yoshikawa, Sadao Suga, Toshihiko Nakashima, Takehiko Yazaki, Minoru Fukuda, Seiji Kojima, Takaharu Matsuyama

Research output: Contribution to journalLetterpeer-review

78 Citations (Scopus)


To the Editor: Human herpesvirus Type 6 (herpesvirus 6) has been isolated from peripheral-blood mononuclear cells of the liver1 and kidney2 of transplant recipients. However, the clinical importance of infection with this virus after organ transplantation is unknown. We report here on infection with herpesvirus 6 in three children with leukemia after bone marrow transplantation. Their clinical and virologic features are summarized in Table 1. All three children had received bone marrow from HLA-matched siblings. Herpesvirus 6 was isolated by coculturing peripheral-blood mononuclear cells from the donors and recipients with phytohemagglutinin-stimulated cord-blood mononuclear cells.3 The virus was isolated from the blood of. .

Original languageEnglish
Pages (from-to)634-635
Number of pages2
JournalNew England Journal of Medicine
Issue number9
Publication statusPublished - 28-02-1991

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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