Real-Time Assessment of Maturity by Microfiber Shaped Ipscs-Derived Cardiac Tissue

Akari Masuda; Shun Itai; Yuta Kurashina; Shugo Tohyama; Hiroaki Onoe

Real-Time Assessment of Maturity by Microfiber Shaped Ipscs-Derived Cardiac Tissue

Akari Masuda, Shun Itai, Yuta Kurashina, Shugo Tohyama, Hiroaki Onoe

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This paper describes a real-time maturity evaluation system of cardiac tissue with a conduction velocity (CV). A microfiber-shaped cardiac tissue enables easy measurement of CVs by the one-way transmission of signals over a long distance. In addition, CVs can be calculated real-time only with a change in fluorescent intensity, thanks to a visualization of electrical conduction by GCaMP. We measured CVs over 6 days to assess the maturation of the same cardiac tissue in real-time. Our system of maturity evaluation would contribute to the development of a matured cardiac model for elucidating the pathology of cardiac diseases and drug effects.

Original language	English
Title of host publication	2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	240-243
Number of pages	4
ISBN (Electronic)	9784886864352
Publication status	Published - 2023
Externally published	Yes
Event	22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023 - Kyoto, Japan Duration: 25-06-2023 → 29-06-2023

Publication series

Name	2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023

Conference

Conference	22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023
Country/Territory	Japan
City	Kyoto
Period	25-06-23 → 29-06-23

All Science Journal Classification (ASJC) codes

Computer Science Applications
Electrical and Electronic Engineering
Control and Optimization
Instrumentation

Cite this

Masuda, A., Itai, S., Kurashina, Y., Tohyama, S., & Onoe, H. (2023). Real-Time Assessment of Maturity by Microfiber Shaped Ipscs-Derived Cardiac Tissue. In 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023 (pp. 240-243). (2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023). Institute of Electrical and Electronics Engineers Inc..

Masuda, Akari ; Itai, Shun ; Kurashina, Yuta et al. / Real-Time Assessment of Maturity by Microfiber Shaped Ipscs-Derived Cardiac Tissue. 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023. Institute of Electrical and Electronics Engineers Inc., 2023. pp. 240-243 (2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023).

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title = "Real-Time Assessment of Maturity by Microfiber Shaped Ipscs-Derived Cardiac Tissue",

abstract = "This paper describes a real-time maturity evaluation system of cardiac tissue with a conduction velocity (CV). A microfiber-shaped cardiac tissue enables easy measurement of CVs by the one-way transmission of signals over a long distance. In addition, CVs can be calculated real-time only with a change in fluorescent intensity, thanks to a visualization of electrical conduction by GCaMP. We measured CVs over 6 days to assess the maturation of the same cardiac tissue in real-time. Our system of maturity evaluation would contribute to the development of a matured cardiac model for elucidating the pathology of cardiac diseases and drug effects.",

author = "Akari Masuda and Shun Itai and Yuta Kurashina and Shugo Tohyama and Hiroaki Onoe",

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year = "2023",

language = "English",

series = "2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023",

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Masuda, A, Itai, S, Kurashina, Y, Tohyama, S & Onoe, H 2023, Real-Time Assessment of Maturity by Microfiber Shaped Ipscs-Derived Cardiac Tissue. in 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023. 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023, Institute of Electrical and Electronics Engineers Inc., pp. 240-243, 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023, Kyoto, Japan, 25-06-23.

Real-Time Assessment of Maturity by Microfiber Shaped Ipscs-Derived Cardiac Tissue. / Masuda, Akari; Itai, Shun; Kurashina, Yuta et al.
2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023. Institute of Electrical and Electronics Engineers Inc., 2023. p. 240-243 (2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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T1 - Real-Time Assessment of Maturity by Microfiber Shaped Ipscs-Derived Cardiac Tissue

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AU - Itai, Shun

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AU - Tohyama, Shugo

AU - Onoe, Hiroaki

PY - 2023

Y1 - 2023

N2 - This paper describes a real-time maturity evaluation system of cardiac tissue with a conduction velocity (CV). A microfiber-shaped cardiac tissue enables easy measurement of CVs by the one-way transmission of signals over a long distance. In addition, CVs can be calculated real-time only with a change in fluorescent intensity, thanks to a visualization of electrical conduction by GCaMP. We measured CVs over 6 days to assess the maturation of the same cardiac tissue in real-time. Our system of maturity evaluation would contribute to the development of a matured cardiac model for elucidating the pathology of cardiac diseases and drug effects.

AB - This paper describes a real-time maturity evaluation system of cardiac tissue with a conduction velocity (CV). A microfiber-shaped cardiac tissue enables easy measurement of CVs by the one-way transmission of signals over a long distance. In addition, CVs can be calculated real-time only with a change in fluorescent intensity, thanks to a visualization of electrical conduction by GCaMP. We measured CVs over 6 days to assess the maturation of the same cardiac tissue in real-time. Our system of maturity evaluation would contribute to the development of a matured cardiac model for elucidating the pathology of cardiac diseases and drug effects.

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M3 - Conference contribution

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T3 - 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023

SP - 240

EP - 243

BT - 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023

Y2 - 25 June 2023 through 29 June 2023

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Masuda A, Itai S, Kurashina Y, Tohyama S, Onoe H. Real-Time Assessment of Maturity by Microfiber Shaped Ipscs-Derived Cardiac Tissue. In 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023. Institute of Electrical and Electronics Engineers Inc. 2023. p. 240-243. (2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023).

Real-Time Assessment of Maturity by Microfiber Shaped Ipscs-Derived Cardiac Tissue

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All Science Journal Classification (ASJC) codes

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