Real-time changes in corticospinal excitability related to motor imagery of a force control task

Tsuyoshi Tatemoto, Junko Tsuchiya, Atsuki Numata, Ryuji Osawa, Tomofumi Yamaguchi, Shigeo Tanabe, Kunitsugu Kondo, Yohei Otaka, Kenichi Sugawara

Research output: Contribution to journalArticle

Abstract

Objective To investigate real-time excitability changes in corticospinal pathways related to motor imagery in a changing force control task, using transcranial magnetic stimulation (TMS). Methods Ten healthy volunteers learnt to control the contractile force of isometric right wrist dorsiflexion in order to track an on-screen sine wave form. Participants performed the trained task 40 times with actual muscle contraction in order to construct the motor image. They were then instructed to execute the task without actual muscle contraction, but by imagining contraction of the right wrist in dorsiflexion. Motor evoked potentials (MEPs), induced by TMS in the right extensor carpi radialis muscle (ECR) and flexor carpi radialis muscle (FCR), were measured during motor imagery. MEPs were induced at five time points: prior to imagery, during the gradual generation of the imaged wrist dorsiflexion (Increasing phase), the peak value of the sine wave, during the gradual reduction (Decreasing phase), and after completion of the task. The MEP ratio, as the ratio of imaged MEPs to resting-state, was compared between pre- and post-training at each time point. Results In the ECR muscle, the MEP ratio significantly increased during the Increasing phase and at the peak force of dorsiflexion imagery after training. Moreover, the MEP ratio was significantly greater in the Increasing phase than in the Decreasing phase. In the FCR, there were no significant consistent changes. Conclusion Corticospinal excitability during motor imagery in an isometric contraction task was modulated in relation to the phase of force control after image construction.

Original languageEnglish
Pages (from-to)185-190
Number of pages6
JournalBehavioural Brain Research
Volume335
DOIs
Publication statusPublished - 29-09-2017

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Motor Evoked Potentials
Imagery (Psychotherapy)
Advisory Committees
Muscles
Wrist
Transcranial Magnetic Stimulation
Muscle Contraction
Isometric Contraction
Healthy Volunteers

All Science Journal Classification (ASJC) codes

  • Behavioral Neuroscience

Cite this

Tatemoto, Tsuyoshi ; Tsuchiya, Junko ; Numata, Atsuki ; Osawa, Ryuji ; Yamaguchi, Tomofumi ; Tanabe, Shigeo ; Kondo, Kunitsugu ; Otaka, Yohei ; Sugawara, Kenichi. / Real-time changes in corticospinal excitability related to motor imagery of a force control task. In: Behavioural Brain Research. 2017 ; Vol. 335. pp. 185-190.
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abstract = "Objective To investigate real-time excitability changes in corticospinal pathways related to motor imagery in a changing force control task, using transcranial magnetic stimulation (TMS). Methods Ten healthy volunteers learnt to control the contractile force of isometric right wrist dorsiflexion in order to track an on-screen sine wave form. Participants performed the trained task 40 times with actual muscle contraction in order to construct the motor image. They were then instructed to execute the task without actual muscle contraction, but by imagining contraction of the right wrist in dorsiflexion. Motor evoked potentials (MEPs), induced by TMS in the right extensor carpi radialis muscle (ECR) and flexor carpi radialis muscle (FCR), were measured during motor imagery. MEPs were induced at five time points: prior to imagery, during the gradual generation of the imaged wrist dorsiflexion (Increasing phase), the peak value of the sine wave, during the gradual reduction (Decreasing phase), and after completion of the task. The MEP ratio, as the ratio of imaged MEPs to resting-state, was compared between pre- and post-training at each time point. Results In the ECR muscle, the MEP ratio significantly increased during the Increasing phase and at the peak force of dorsiflexion imagery after training. Moreover, the MEP ratio was significantly greater in the Increasing phase than in the Decreasing phase. In the FCR, there were no significant consistent changes. Conclusion Corticospinal excitability during motor imagery in an isometric contraction task was modulated in relation to the phase of force control after image construction.",
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Real-time changes in corticospinal excitability related to motor imagery of a force control task. / Tatemoto, Tsuyoshi; Tsuchiya, Junko; Numata, Atsuki; Osawa, Ryuji; Yamaguchi, Tomofumi; Tanabe, Shigeo; Kondo, Kunitsugu; Otaka, Yohei; Sugawara, Kenichi.

In: Behavioural Brain Research, Vol. 335, 29.09.2017, p. 185-190.

Research output: Contribution to journalArticle

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AU - Tatemoto, Tsuyoshi

AU - Tsuchiya, Junko

AU - Numata, Atsuki

AU - Osawa, Ryuji

AU - Yamaguchi, Tomofumi

AU - Tanabe, Shigeo

AU - Kondo, Kunitsugu

AU - Otaka, Yohei

AU - Sugawara, Kenichi

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Y1 - 2017/9/29

N2 - Objective To investigate real-time excitability changes in corticospinal pathways related to motor imagery in a changing force control task, using transcranial magnetic stimulation (TMS). Methods Ten healthy volunteers learnt to control the contractile force of isometric right wrist dorsiflexion in order to track an on-screen sine wave form. Participants performed the trained task 40 times with actual muscle contraction in order to construct the motor image. They were then instructed to execute the task without actual muscle contraction, but by imagining contraction of the right wrist in dorsiflexion. Motor evoked potentials (MEPs), induced by TMS in the right extensor carpi radialis muscle (ECR) and flexor carpi radialis muscle (FCR), were measured during motor imagery. MEPs were induced at five time points: prior to imagery, during the gradual generation of the imaged wrist dorsiflexion (Increasing phase), the peak value of the sine wave, during the gradual reduction (Decreasing phase), and after completion of the task. The MEP ratio, as the ratio of imaged MEPs to resting-state, was compared between pre- and post-training at each time point. Results In the ECR muscle, the MEP ratio significantly increased during the Increasing phase and at the peak force of dorsiflexion imagery after training. Moreover, the MEP ratio was significantly greater in the Increasing phase than in the Decreasing phase. In the FCR, there were no significant consistent changes. Conclusion Corticospinal excitability during motor imagery in an isometric contraction task was modulated in relation to the phase of force control after image construction.

AB - Objective To investigate real-time excitability changes in corticospinal pathways related to motor imagery in a changing force control task, using transcranial magnetic stimulation (TMS). Methods Ten healthy volunteers learnt to control the contractile force of isometric right wrist dorsiflexion in order to track an on-screen sine wave form. Participants performed the trained task 40 times with actual muscle contraction in order to construct the motor image. They were then instructed to execute the task without actual muscle contraction, but by imagining contraction of the right wrist in dorsiflexion. Motor evoked potentials (MEPs), induced by TMS in the right extensor carpi radialis muscle (ECR) and flexor carpi radialis muscle (FCR), were measured during motor imagery. MEPs were induced at five time points: prior to imagery, during the gradual generation of the imaged wrist dorsiflexion (Increasing phase), the peak value of the sine wave, during the gradual reduction (Decreasing phase), and after completion of the task. The MEP ratio, as the ratio of imaged MEPs to resting-state, was compared between pre- and post-training at each time point. Results In the ECR muscle, the MEP ratio significantly increased during the Increasing phase and at the peak force of dorsiflexion imagery after training. Moreover, the MEP ratio was significantly greater in the Increasing phase than in the Decreasing phase. In the FCR, there were no significant consistent changes. Conclusion Corticospinal excitability during motor imagery in an isometric contraction task was modulated in relation to the phase of force control after image construction.

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