Abstract
Systemic sclerosis (SSc) is a disorder characterized by immune dysfunction, microvascular injury, and fibrosis. Organ involvement in patients with SSc is variable; however, pulmonary involvement occurs in up to 90% of patients with SSc. Interstitial lung disease (ILD) is a major cause of mortality and, thus, a major determinant in the prognosis of patients with SSc. This review summarizes current findings about the characteristics of ILD in patients with SSc, selection of patients with SSc-ILD who are candidates for the treatment, and current treatment options.
Original language | English |
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Pages (from-to) | 97-110 |
Number of pages | 14 |
Journal | Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine |
Volume | 9 |
DOIs | |
Publication status | Published - 19-01-2016 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Pulmonary and Respiratory Medicine
- Cardiology and Cardiovascular Medicine