Reconstitution of γ-secretase by truncated presenilin (PS) fragments revealed that PS C-terminal transmembrane domain is critical for formation of γ-secretase complex

Hirohisa Shiraishi, Toshihiro Marutani, Hua Qin Wang, Yasuhiro Maeda, Yukihisa Kurono, Akihiko Takashima, Wataru Araki, Masaki Nishimura, Katsuhiko Yanagisawa, Hiroto Komano

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Biochemistry, Genetics and Molecular Biology

Medicine and Dentistry