Recovery and maintenance of copper levels in geriatric patients on enteral feeding for a prolonged period

Yuki Ito, Tetsuo Ando, Toshitaka Nabeshima

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Latent copper deficiency develops after 3 mo in patients receiving enteral feeding solutions with low copper levels. We examined whether a copper-rich enteral solution restores and maintains the level of copper in serum for a prolonged period. The study group consisted of 13 patients (eight males and five females). Commercial preparations, F2α® and Lifelon-PZ®, for enteral administration were used. F2α® and Lifelon-PZ® contain 1.6 and 0.13 mg/L, respectively, of copper. Serum copper levels were monitored in patients before and after administration of F2α®, a copper-rich enteral solution, at the neurological ward of Nagoya Daini Red Cross Hospital. Four of the 13 patients received Liflon-PZ®, a copper-poor enteral solution, before this trial. Blood samples were taken every month. The daily average copper dosage with F2α® was 1.8±0.4mg/d (1.0-2.4 mg/d). The copper level in the four patients who received Liflon-PZ® was 10.5 ±5.5 μmol/L before this trial. The level rose to 18.9±3.6 μmol/L 1 mo after the change to the copper-rich, F2α®. The average serum copper level in the other patients before the start of enteral feeding was 15.3±5.0 μmol/L. The proper copper level was maintained with F2α® in the long term. A copper-rich enteral preparation could easily restore and maintain serum copper levels for a prolonged period. A dose of 1.8±0.4 mg copper/d (1.0-2.4 mg/d) was sufficient for our patients.

Original languageEnglish
Pages (from-to)200-204
Number of pages5
JournalJournal of Nutritional Science and Vitaminology
Volume52
Issue number3
DOIs
Publication statusPublished - 01-06-2006

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Enteral Nutrition
Geriatrics
Copper
Maintenance
Small Intestine
Serum
Red Cross

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

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title = "Recovery and maintenance of copper levels in geriatric patients on enteral feeding for a prolonged period",
abstract = "Latent copper deficiency develops after 3 mo in patients receiving enteral feeding solutions with low copper levels. We examined whether a copper-rich enteral solution restores and maintains the level of copper in serum for a prolonged period. The study group consisted of 13 patients (eight males and five females). Commercial preparations, F2α{\circledR} and Lifelon-PZ{\circledR}, for enteral administration were used. F2α{\circledR} and Lifelon-PZ{\circledR} contain 1.6 and 0.13 mg/L, respectively, of copper. Serum copper levels were monitored in patients before and after administration of F2α{\circledR}, a copper-rich enteral solution, at the neurological ward of Nagoya Daini Red Cross Hospital. Four of the 13 patients received Liflon-PZ{\circledR}, a copper-poor enteral solution, before this trial. Blood samples were taken every month. The daily average copper dosage with F2α{\circledR} was 1.8±0.4mg/d (1.0-2.4 mg/d). The copper level in the four patients who received Liflon-PZ{\circledR} was 10.5 ±5.5 μmol/L before this trial. The level rose to 18.9±3.6 μmol/L 1 mo after the change to the copper-rich, F2α{\circledR}. The average serum copper level in the other patients before the start of enteral feeding was 15.3±5.0 μmol/L. The proper copper level was maintained with F2α{\circledR} in the long term. A copper-rich enteral preparation could easily restore and maintain serum copper levels for a prolonged period. A dose of 1.8±0.4 mg copper/d (1.0-2.4 mg/d) was sufficient for our patients.",
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Recovery and maintenance of copper levels in geriatric patients on enteral feeding for a prolonged period. / Ito, Yuki; Ando, Tetsuo; Nabeshima, Toshitaka.

In: Journal of Nutritional Science and Vitaminology, Vol. 52, No. 3, 01.06.2006, p. 200-204.

Research output: Contribution to journalArticle

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