Abstract
We describe a 54-year old woman with oxaliplatin-induced autoimmune hemolytic anemia and review the clinical features of similar published cases. The present patient had metastatic colon cancer and was admitted to our hospital with a floating sensation and general malaise on day 4 after undergoing the last of 4 cycles of a 7 th round of chemotherapy with XELOX. Laboratory data revealed 4.6g/d/ hemoglobin and 8.77 mg/d/ creatinine. Direct and indirect Coombs tests of a blood sample for blood transfusion were both positive. We diagnosed immune hemolysis with acute renal failure based on the clinical course and blood samples showing haptoglobin <10mg/d/. We treated her with hemodialysis, plasmapheresis and immune suppression with prednisolone, which improved the anemia and renal failure.
| Original language | English |
|---|---|
| Pages (from-to) | 1712-1719 |
| Number of pages | 8 |
| Journal | Journal of Japanese Society of Gastroenterology |
| Volume | 108 |
| Issue number | 10 |
| Publication status | Published - 10-2011 |
All Science Journal Classification (ASJC) codes
- Gastroenterology
