Metastasis to the small intestine presents occasionally as multiple lesions and is associated with numerous complications. However, metastasis-induced intussusception in adults is a rare phenomenon. We report a case of recurrent intussusception induced by metastatic lesions from lung cancer. A 54-year-old male was referred to our hospital with intermittent lower right abdominal pain. Chest computed tomography (CT) revealed a mass, suggesting lung cancer, and abdominal CT showed characteristic target-shaped lesions highly suggestive of enteric intussusception in the ileum. The patient underwent segmental resection of the intussuscepted ileum, and analysis of the resected specimen identified a poorly differentiated adenocarcinoma that was pathologically and immunohistologically identical to the lung specimen obtained by percutaneous needle biopsy. Although the symptoms transiently resolved after surgery, intussusception recurred 3 weeks later, and the patient died 28 days after surgery. Multiple metastatic lesions should be considered in adult intussusception, particularly in patients with a history of malignancy.
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