Reduction of severe acute respiratory syndrome coronavirus-2 infectivity by admissible concentration of ozone gas and water

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Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing the global coronavirus disease 2019 (COVID-19) pandemic. Because complete elimination of SARS-CoV-2 appears difficult, decreasing the risk of transmission is important. Treatment with 0.1 and 0.05 ppm ozone gas for 10 and 20 hr, respectively, decreased SARS-CoV-2 infectivity by about 95%. The magnitude of the effect was dependent on humidity. Treatment with 1 and 2 mg/L ozone water for 10 s reduced SARS-CoV-2 infectivity by about 2 and 3 logs, respectively. Our results suggest that low-dose ozone, in the form of gas and water, is effective against SARS-CoV-2.

Original languageEnglish
Pages (from-to)10-16
Number of pages7
JournalMICROBIOLOGY and IMMUNOLOGY
Volume65
Issue number1
DOIs
Publication statusPublished - 01-2021

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Virology

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