TY - JOUR
T1 - Reduction of severe acute respiratory syndrome coronavirus-2 infectivity by admissible concentration of ozone gas and water
AU - Murata, Takayuki
AU - Komoto, Satoshi
AU - Iwahori, Satoko
AU - Sasaki, Jun
AU - Nishitsuji, Hironori
AU - Hasebe, Terumitsu
AU - Hoshinaga, Kiyotaka
AU - Yuzawa, Yukio
N1 - Funding Information:
We thank Shunya Ito (Institute of Medical Information Inc.), Tamura TECO Co. Ltd, Drs. Masahide Takahashi, Yasuharu Niwa (International Regenerative Medicine Center, Fujita Health University), Yusuke Minato, and Yohei Doi (Department of Microbiology, Fujita Health University) for technical assistance and discussions.
Publisher Copyright:
© 2020 The Societies and John Wiley & Sons Australia, Ltd
PY - 2021/1
Y1 - 2021/1
N2 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing the global coronavirus disease 2019 (COVID-19) pandemic. Because complete elimination of SARS-CoV-2 appears difficult, decreasing the risk of transmission is important. Treatment with 0.1 and 0.05 ppm ozone gas for 10 and 20 hr, respectively, decreased SARS-CoV-2 infectivity by about 95%. The magnitude of the effect was dependent on humidity. Treatment with 1 and 2 mg/L ozone water for 10 s reduced SARS-CoV-2 infectivity by about 2 and 3 logs, respectively. Our results suggest that low-dose ozone, in the form of gas and water, is effective against SARS-CoV-2.
AB - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing the global coronavirus disease 2019 (COVID-19) pandemic. Because complete elimination of SARS-CoV-2 appears difficult, decreasing the risk of transmission is important. Treatment with 0.1 and 0.05 ppm ozone gas for 10 and 20 hr, respectively, decreased SARS-CoV-2 infectivity by about 95%. The magnitude of the effect was dependent on humidity. Treatment with 1 and 2 mg/L ozone water for 10 s reduced SARS-CoV-2 infectivity by about 2 and 3 logs, respectively. Our results suggest that low-dose ozone, in the form of gas and water, is effective against SARS-CoV-2.
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U2 - 10.1111/1348-0421.12861
DO - 10.1111/1348-0421.12861
M3 - Article
C2 - 33230863
AN - SCOPUS:85097489248
SN - 0385-5600
VL - 65
SP - 10
EP - 16
JO - MICROBIOLOGY and IMMUNOLOGY
JF - MICROBIOLOGY and IMMUNOLOGY
IS - 1
ER -