Reduction of severe acute respiratory syndrome coronavirus-2 infectivity by admissible concentration of ozone gas and water

Takayuki Murata; Satoshi Komoto; Satoko Iwahori; Jun Sasaki; Hironori Nishitsuji; Terumitsu Hasebe; Kiyotaka Hoshinaga; Yukio Yuzawa

doi:10.1111/1348-0421.12861

Reduction of severe acute respiratory syndrome coronavirus-2 infectivity by admissible concentration of ozone gas and water

Takayuki Murata, Satoshi Komoto, Satoko Iwahori, Jun Sasaki, Hironori Nishitsuji, Terumitsu Hasebe, Kiyotaka Hoshinaga, Yukio Yuzawa

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing the global coronavirus disease 2019 (COVID-19) pandemic. Because complete elimination of SARS-CoV-2 appears difficult, decreasing the risk of transmission is important. Treatment with 0.1 and 0.05 ppm ozone gas for 10 and 20 hr, respectively, decreased SARS-CoV-2 infectivity by about 95%. The magnitude of the effect was dependent on humidity. Treatment with 1 and 2 mg/L ozone water for 10 s reduced SARS-CoV-2 infectivity by about 2 and 3 logs, respectively. Our results suggest that low-dose ozone, in the form of gas and water, is effective against SARS-CoV-2.

Original language	English
Pages (from-to)	10-16
Number of pages	7
Journal	MICROBIOLOGY and IMMUNOLOGY
Volume	65
Issue number	1
DOIs	https://doi.org/10.1111/1348-0421.12861
Publication status	Published - 01-2021
Externally published	Yes

All Science Journal Classification (ASJC) codes

Microbiology
Immunology
Virology

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10.1111/1348-0421.12861

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title = "Reduction of severe acute respiratory syndrome coronavirus-2 infectivity by admissible concentration of ozone gas and water",

abstract = "Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing the global coronavirus disease 2019 (COVID-19) pandemic. Because complete elimination of SARS-CoV-2 appears difficult, decreasing the risk of transmission is important. Treatment with 0.1 and 0.05 ppm ozone gas for 10 and 20 hr, respectively, decreased SARS-CoV-2 infectivity by about 95%. The magnitude of the effect was dependent on humidity. Treatment with 1 and 2 mg/L ozone water for 10 s reduced SARS-CoV-2 infectivity by about 2 and 3 logs, respectively. Our results suggest that low-dose ozone, in the form of gas and water, is effective against SARS-CoV-2.",

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T1 - Reduction of severe acute respiratory syndrome coronavirus-2 infectivity by admissible concentration of ozone gas and water

AU - Murata, Takayuki

AU - Komoto, Satoshi

AU - Iwahori, Satoko

AU - Sasaki, Jun

AU - Nishitsuji, Hironori

AU - Hasebe, Terumitsu

AU - Hoshinaga, Kiyotaka

AU - Yuzawa, Yukio

PY - 2021/1

Y1 - 2021/1

N2 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing the global coronavirus disease 2019 (COVID-19) pandemic. Because complete elimination of SARS-CoV-2 appears difficult, decreasing the risk of transmission is important. Treatment with 0.1 and 0.05 ppm ozone gas for 10 and 20 hr, respectively, decreased SARS-CoV-2 infectivity by about 95%. The magnitude of the effect was dependent on humidity. Treatment with 1 and 2 mg/L ozone water for 10 s reduced SARS-CoV-2 infectivity by about 2 and 3 logs, respectively. Our results suggest that low-dose ozone, in the form of gas and water, is effective against SARS-CoV-2.

AB - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing the global coronavirus disease 2019 (COVID-19) pandemic. Because complete elimination of SARS-CoV-2 appears difficult, decreasing the risk of transmission is important. Treatment with 0.1 and 0.05 ppm ozone gas for 10 and 20 hr, respectively, decreased SARS-CoV-2 infectivity by about 95%. The magnitude of the effect was dependent on humidity. Treatment with 1 and 2 mg/L ozone water for 10 s reduced SARS-CoV-2 infectivity by about 2 and 3 logs, respectively. Our results suggest that low-dose ozone, in the form of gas and water, is effective against SARS-CoV-2.

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KW - humidity

KW - ozone gas

KW - ozone water

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Reduction of severe acute respiratory syndrome coronavirus-2 infectivity by admissible concentration of ozone gas and water

Abstract

All Science Journal Classification (ASJC) codes

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