Regeneration-based therapies for spinal cord injuries

Hideyuki Okano; Shinjiro Kaneko; Seiji Okada; Akio Iwanami; Masaya Nakamura; Yoshiaki Toyama

doi:10.1016/j.neuint.2007.04.013

Regeneration-based therapies for spinal cord injuries

Hideyuki Okano
, Shinjiro Kaneko
, Seiji Okada
, Akio Iwanami
, Masaya Nakamura
, Yoshiaki Toyama

Research output: Contribution to journal › Review article › peer-review

26 Citations (Scopus)

Abstract

Although it has been long believed that the damaged central nervous system does not regenerate upon injury, there is an emerging hope for regeneration-based therapy of the damaged central nervous system (CNS) due to the progress of developmental biology and regenerative medicine including stem cell biology. In this review, we have summarized recent studies aimed at the development of regeneration-based therapeutic approaches for spinal cord injuries, including therapy with anti-inflammatory cytokines, transplantation of neural stem/precursor cells and induction of axonal regeneration.

Original language	English
Pages (from-to)	68-73
Number of pages	6
Journal	Neurochemistry International
Volume	51
Issue number	2-4 SPEC. ISS.
DOIs	https://doi.org/10.1016/j.neuint.2007.04.013
Publication status	Published - 07-2007
Externally published	Yes

All Science Journal Classification (ASJC) codes

Cellular and Molecular Neuroscience
Cell Biology

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10.1016/j.neuint.2007.04.013

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title = "Regeneration-based therapies for spinal cord injuries",

abstract = "Although it has been long believed that the damaged central nervous system does not regenerate upon injury, there is an emerging hope for regeneration-based therapy of the damaged central nervous system (CNS) due to the progress of developmental biology and regenerative medicine including stem cell biology. In this review, we have summarized recent studies aimed at the development of regeneration-based therapeutic approaches for spinal cord injuries, including therapy with anti-inflammatory cytokines, transplantation of neural stem/precursor cells and induction of axonal regeneration.",

author = "Hideyuki Okano and Shinjiro Kaneko and Seiji Okada and Akio Iwanami and Masaya Nakamura and Yoshiaki Toyama",

note = "Funding Information: We are grateful to the members of the Okano Laboratory for their comments on the manuscript. This work was supported by a grant from Solution-Oriented Research for Science and Technology (SORST), Japan Science and Technology Agency (JST) and those from the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan; the Japan Science and Technology Corporation (JST)",

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language = "English",

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T1 - Regeneration-based therapies for spinal cord injuries

AU - Okano, Hideyuki

AU - Kaneko, Shinjiro

AU - Okada, Seiji

AU - Iwanami, Akio

AU - Nakamura, Masaya

AU - Toyama, Yoshiaki

N1 - Funding Information: We are grateful to the members of the Okano Laboratory for their comments on the manuscript. This work was supported by a grant from Solution-Oriented Research for Science and Technology (SORST), Japan Science and Technology Agency (JST) and those from the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan; the Japan Science and Technology Corporation (JST)

PY - 2007/7

Y1 - 2007/7

N2 - Although it has been long believed that the damaged central nervous system does not regenerate upon injury, there is an emerging hope for regeneration-based therapy of the damaged central nervous system (CNS) due to the progress of developmental biology and regenerative medicine including stem cell biology. In this review, we have summarized recent studies aimed at the development of regeneration-based therapeutic approaches for spinal cord injuries, including therapy with anti-inflammatory cytokines, transplantation of neural stem/precursor cells and induction of axonal regeneration.

AB - Although it has been long believed that the damaged central nervous system does not regenerate upon injury, there is an emerging hope for regeneration-based therapy of the damaged central nervous system (CNS) due to the progress of developmental biology and regenerative medicine including stem cell biology. In this review, we have summarized recent studies aimed at the development of regeneration-based therapeutic approaches for spinal cord injuries, including therapy with anti-inflammatory cytokines, transplantation of neural stem/precursor cells and induction of axonal regeneration.

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DO - 10.1016/j.neuint.2007.04.013

M3 - Review article

C2 - 17544171

AN - SCOPUS:34547459568

SN - 0197-0186

VL - 51

SP - 68

EP - 73

JO - Neurochemistry International

JF - Neurochemistry International

IS - 2-4 SPEC. ISS.

ER -

Regeneration-based therapies for spinal cord injuries

Abstract

All Science Journal Classification (ASJC) codes

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