Regression of a large lipid-rich pool in the coronary artery during treatment with statin detected by intravascular ultrasound: A case report

Hiroaki Takashima, Tatsuya Yasukawa, Yukio Ozaki, Kenji Asai, Hiroyuki Shinjo, Katsuhisa Waseda, Yasuo Kuroda, Yoshinori Wakita, Takashi Kosaka, Yasushi Kuhara, Takayuki Ito

Research output: Contribution to journalArticle

Abstract

A 54-year-old man with unstable angina presented with severe stenosis of the middle segment of the left anterior descending coronary artery. Percutaneous coronary stent implantation and serial intravascular ultrasound (IVUS) were performed. IVUS detected a non-culprit coronary plaque with a large lipid-rich pool in the proximal segment of the left anterior descending coronary artery. Atorvastatin 10 mg/day was given to reduce his cholesterol level for 2 years after the stent implantation. This patient had no cardiac events, and the low-density lipoprotein-cholesterol level reduced from 171 to 88 mg/d/at follow-up. Two-year follow-up IVUS examination revealed the reduction of plaque burden associated with regression of the lipid-rich pool size. This case may indicate that statin could contribute to the regression of lipid-rich plaque and to the stability of coronary plaque.

Original languageEnglish
Pages (from-to)307-312
Number of pages6
JournalJournal of Cardiology
Volume47
Issue number6
Publication statusPublished - 01-12-2006

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Hydroxymethylglutaryl-CoA Reductase Inhibitors
Coronary Vessels
Lipids
Stents
Unstable Angina
LDL Cholesterol
Pathologic Constriction
Therapeutics
Cholesterol

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Takashima, Hiroaki ; Yasukawa, Tatsuya ; Ozaki, Yukio ; Asai, Kenji ; Shinjo, Hiroyuki ; Waseda, Katsuhisa ; Kuroda, Yasuo ; Wakita, Yoshinori ; Kosaka, Takashi ; Kuhara, Yasushi ; Ito, Takayuki. / Regression of a large lipid-rich pool in the coronary artery during treatment with statin detected by intravascular ultrasound : A case report. In: Journal of Cardiology. 2006 ; Vol. 47, No. 6. pp. 307-312.
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abstract = "A 54-year-old man with unstable angina presented with severe stenosis of the middle segment of the left anterior descending coronary artery. Percutaneous coronary stent implantation and serial intravascular ultrasound (IVUS) were performed. IVUS detected a non-culprit coronary plaque with a large lipid-rich pool in the proximal segment of the left anterior descending coronary artery. Atorvastatin 10 mg/day was given to reduce his cholesterol level for 2 years after the stent implantation. This patient had no cardiac events, and the low-density lipoprotein-cholesterol level reduced from 171 to 88 mg/d/at follow-up. Two-year follow-up IVUS examination revealed the reduction of plaque burden associated with regression of the lipid-rich pool size. This case may indicate that statin could contribute to the regression of lipid-rich plaque and to the stability of coronary plaque.",
author = "Hiroaki Takashima and Tatsuya Yasukawa and Yukio Ozaki and Kenji Asai and Hiroyuki Shinjo and Katsuhisa Waseda and Yasuo Kuroda and Yoshinori Wakita and Takashi Kosaka and Yasushi Kuhara and Takayuki Ito",
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Takashima, H, Yasukawa, T, Ozaki, Y, Asai, K, Shinjo, H, Waseda, K, Kuroda, Y, Wakita, Y, Kosaka, T, Kuhara, Y & Ito, T 2006, 'Regression of a large lipid-rich pool in the coronary artery during treatment with statin detected by intravascular ultrasound: A case report', Journal of Cardiology, vol. 47, no. 6, pp. 307-312.

Regression of a large lipid-rich pool in the coronary artery during treatment with statin detected by intravascular ultrasound : A case report. / Takashima, Hiroaki; Yasukawa, Tatsuya; Ozaki, Yukio; Asai, Kenji; Shinjo, Hiroyuki; Waseda, Katsuhisa; Kuroda, Yasuo; Wakita, Yoshinori; Kosaka, Takashi; Kuhara, Yasushi; Ito, Takayuki.

In: Journal of Cardiology, Vol. 47, No. 6, 01.12.2006, p. 307-312.

Research output: Contribution to journalArticle

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T1 - Regression of a large lipid-rich pool in the coronary artery during treatment with statin detected by intravascular ultrasound

T2 - A case report

AU - Takashima, Hiroaki

AU - Yasukawa, Tatsuya

AU - Ozaki, Yukio

AU - Asai, Kenji

AU - Shinjo, Hiroyuki

AU - Waseda, Katsuhisa

AU - Kuroda, Yasuo

AU - Wakita, Yoshinori

AU - Kosaka, Takashi

AU - Kuhara, Yasushi

AU - Ito, Takayuki

PY - 2006/12/1

Y1 - 2006/12/1

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