Relapsing Hypoglycemia Associated with Hypocarnitinemia Following Treatment with Cefcapene Pivoxil in an Elderly Man

Shogo Hanai, Mitsunaga Iwata, Teruhiko Terasawa

Research output: Contribution to journalArticle

Abstract

Pivoxil-containing cephalosporins can result in symptomatic hypocarnitinemia in children. We herein report a case of an 85-year-old man at risk of carnitine deficiency who developed relapsing symptomatic hypoglycemia after treatment with cefcapene pivoxil for urinary tract infection. On admission, laboratory tests showed low blood carnitine concentrations with low normal blood ketone levels. The patient was successfully treated by the oral administration of levocarnitine and dietary modification, including aggressive consumption of meat and dairy products, and remained symptom-free for nine months after the correction of carnitine concentrations. Healthcare providers should be cautious when prescribing pivoxil-containing antimicrobials to patients at high risk of hypocarnitinemia.

Original languageEnglish
Pages (from-to)2891-2894
Number of pages4
JournalInternal medicine (Tokyo, Japan)
Volume58
Issue number19
DOIs
Publication statusPublished - 01-10-2019

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Carnitine
Hypoglycemia
Diet Therapy
Meat Products
Dairy Products
Cephalosporins
Therapeutics
Ketones
Urinary Tract Infections
Health Personnel
Oral Administration

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

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abstract = "Pivoxil-containing cephalosporins can result in symptomatic hypocarnitinemia in children. We herein report a case of an 85-year-old man at risk of carnitine deficiency who developed relapsing symptomatic hypoglycemia after treatment with cefcapene pivoxil for urinary tract infection. On admission, laboratory tests showed low blood carnitine concentrations with low normal blood ketone levels. The patient was successfully treated by the oral administration of levocarnitine and dietary modification, including aggressive consumption of meat and dairy products, and remained symptom-free for nine months after the correction of carnitine concentrations. Healthcare providers should be cautious when prescribing pivoxil-containing antimicrobials to patients at high risk of hypocarnitinemia.",
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Relapsing Hypoglycemia Associated with Hypocarnitinemia Following Treatment with Cefcapene Pivoxil in an Elderly Man. / Hanai, Shogo; Iwata, Mitsunaga; Terasawa, Teruhiko.

In: Internal medicine (Tokyo, Japan), Vol. 58, No. 19, 01.10.2019, p. 2891-2894.

Research output: Contribution to journalArticle

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