Relation of CAVI (Cardio ankle vascular index) and NT-proBNP in diabetic retinopathy

Akihiro Yoshida, Masaaki Kouwaki, Masaki Makino, Kentarou Fujiwara, Michitaka Naito

Research output: Contribution to journalArticlepeer-review

Abstract

Vascular lesions accompanying diabetes mellitus are closely related to atherosclerosis onset and progression, so we studied the relationship between the cardioankle vascular index (CAVI) and of NT-proBNP and metabolic syndrome and of atherosclerosis risk markers. We divided the diabetic retinopathy of 69 subjects with type 2 diabetes mellitus into three groups normal (N), simple retinopathy (S), and proliferative retinopathy (P). The CAVI, a stiffness index, and NT-proBNP, a cardiac function index, increased as retinopathy progressed and NT-proBNP correlated significantly with R-CAVI (r = 0.401, p = 0.0006) and L-CAVI (r = 0.450. p<0.0001). Our results suggest that the increase in CAVI and NT-proBNP in subjects with diabetic retinopathy is a useful index of atherosclerosis progression and cardiovascular function.

Original languageEnglish
Pages (from-to)90-94
Number of pages5
JournalJournal of the Japan Diabetes Society
Volume53
Issue number2
Publication statusPublished - 01-02-2010
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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