Vascular lesions accompanying diabetes mellitus are closely related to atherosclerosis onset and progression, so we studied the relationship between the cardioankle vascular index (CAVI) and of NT-proBNP and metabolic syndrome and of atherosclerosis risk markers. We divided the diabetic retinopathy of 69 subjects with type 2 diabetes mellitus into three groups normal (N), simple retinopathy (S), and proliferative retinopathy (P). The CAVI, a stiffness index, and NT-proBNP, a cardiac function index, increased as retinopathy progressed and NT-proBNP correlated significantly with R-CAVI (r = 0.401, p = 0.0006) and L-CAVI (r = 0.450. p<0.0001). Our results suggest that the increase in CAVI and NT-proBNP in subjects with diabetic retinopathy is a useful index of atherosclerosis progression and cardiovascular function.
|Number of pages||5|
|Journal||Journal of the Japan Diabetes Society|
|Publication status||Published - 01-02-2010|
All Science Journal Classification (ASJC) codes
- Internal Medicine
- Endocrinology, Diabetes and Metabolism