TY - JOUR
T1 - Relationship between Alcohol Intake and Chronic Pain with Depressive Symptoms
T2 - A Cross-Sectional Analysis of the Shika Study
AU - Amatsu, Takashi
AU - Tsujiguchi, Hiromasa
AU - Hara, Akinori
AU - Miyagi, Sakae
AU - Kannon, Takayuki
AU - Suzuki, Keita
AU - Shimizu, Yukari
AU - Nguyen, Thao Thi Thu
AU - Pham, Kim Oanh
AU - Suzuki, Fumihiko
AU - Kasahara, Tomoko
AU - Nakamura, Masaharu
AU - Hayashi, Koichiro
AU - Shibata, Aki
AU - Ogino, Noriyoshi
AU - Konoshita, Tadashi
AU - Kambayashi, Yasuhiro
AU - Tsuboi, Hirohito
AU - Tajima, Atsushi
AU - Nakamura, Hiroyuki
N1 - Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/2/1
Y1 - 2022/2/1
N2 - Although alcohol intake is associated with chronic pain (CP) and analgesia, epidemiological studies have not yet examined the factors affecting the relationship between alcohol intake and CP in detail. Therefore, the present cross-sectional study investigated the relationship between alcohol intake and CP in community-dwelling middle-aged and elderly individuals with/without depressive symptoms. Participants comprised 2223 inhabitants of Shika town in Ishikawa prefecture, located on the Noto Peninsula facing the Sea of Japan, and included 1007 males and 1216 females. CP, depressive symptoms, and alcohol intake were assessed using a CP questionnaire, the Geriatric Depression Scale-15 and the brief-type self-administered diet history questionnaire, respectively. In males without depressive symptoms, mean alcohol intake was significantly higher at 5.70% energy (27.92 g/day) in the CP group than that of 3.75% energy (20.00 g/day) in the non-CP group. The prevalence of low back/knee pain was also significantly higher in males with than in those without depressive symptoms. The present results suggest that long-term alcohol intake is related to CP by reducing the pain threshold and enhancing nociceptive pain as a possible mechanism. However, even a low alcohol intake was associated with psychogenic pain in participants with depressive symptoms. Further studies to investigate the involvement of depressive symptoms and alcohol intake in CP and its prevention are needed.
AB - Although alcohol intake is associated with chronic pain (CP) and analgesia, epidemiological studies have not yet examined the factors affecting the relationship between alcohol intake and CP in detail. Therefore, the present cross-sectional study investigated the relationship between alcohol intake and CP in community-dwelling middle-aged and elderly individuals with/without depressive symptoms. Participants comprised 2223 inhabitants of Shika town in Ishikawa prefecture, located on the Noto Peninsula facing the Sea of Japan, and included 1007 males and 1216 females. CP, depressive symptoms, and alcohol intake were assessed using a CP questionnaire, the Geriatric Depression Scale-15 and the brief-type self-administered diet history questionnaire, respectively. In males without depressive symptoms, mean alcohol intake was significantly higher at 5.70% energy (27.92 g/day) in the CP group than that of 3.75% energy (20.00 g/day) in the non-CP group. The prevalence of low back/knee pain was also significantly higher in males with than in those without depressive symptoms. The present results suggest that long-term alcohol intake is related to CP by reducing the pain threshold and enhancing nociceptive pain as a possible mechanism. However, even a low alcohol intake was associated with psychogenic pain in participants with depressive symptoms. Further studies to investigate the involvement of depressive symptoms and alcohol intake in CP and its prevention are needed.
KW - Alcohol intake
KW - Brief-type self-administered diet history questionnaire (BDHQ)
KW - Chronic pain
KW - Epidemiology
KW - Geriatric Depression Scale-15 (GDS-15)
UR - https://www.scopus.com/pages/publications/85124303879
UR - https://www.scopus.com/pages/publications/85124303879#tab=citedBy
U2 - 10.3390/ijerph19042024
DO - 10.3390/ijerph19042024
M3 - Article
C2 - 35206213
AN - SCOPUS:85124303879
SN - 1661-7827
VL - 19
JO - International Journal of Environmental Research and Public Health
JF - International Journal of Environmental Research and Public Health
IS - 4
M1 - 2024
ER -
