TY - JOUR
T1 - Relationship Between Each of the Four Major Motor Symptoms and At-Home Physical Activity in Individuals with Parkinson’s Disease
T2 - A Cross-Sectional Study
AU - Hirakawa, Yuichi
AU - Sakurai, Hiroaki
AU - Takeda, Kazuya
AU - Koyama, Soichiro
AU - Iwai, Masanobu
AU - Motoya, Ikuo
AU - Kanada, Yoshikiyo
AU - Kawamura, Nobutoshi
AU - Kawamura, Mami
AU - Tanabe, Shigeo
N1 - Publisher Copyright:
© 2025 by the authors.
PY - 2025/9
Y1 - 2025/9
N2 - Background/Objectives: Individuals with Parkinson’s disease (PD) often experience four major motor symptoms—tremor, rigidity, bradykinesia, and postural instability/gait disorder. Although these symptoms have been shown to affect activities of daily living, their impact on the level of at-home physical activity (PA) in this population remains unexplored. We aimed to investigate the relationship between the four major motor symptoms of PD and at-home PA in these individuals. Methods: This retrospective cross-sectional study included 17 individuals with PD. We examined the relationship between the Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale Part 3 score and the time spent in three PA intensities (sedentary behavior, light PA [LPA], and moderate-to-vigorous PA) within the home. Pearson’s correlation coefficient was used for statistical analysis. Results: In the initial step analysis, a significant negative correlation was observed between the overall motor symptom score and the time spent in LPA inside the home (rs [95% confidence interval]: −0.72 [−0.93 to −0.25]; p < 0.01). In the second step analysis, a significant negative correlation was observed between the bradykinesia score and the time spent in LPA inside the home (rs: −0.74 [−0.92 to −0.30]; p < 0.01). Conclusions: Among the four major motor symptoms, only the severity of bradykinesia influenced the time spent in LPA inside the home. Thus, rehabilitation treatment focusing on bradykinesia may be beneficial for increasing the time spent in LPA inside the home for individuals with PD.
AB - Background/Objectives: Individuals with Parkinson’s disease (PD) often experience four major motor symptoms—tremor, rigidity, bradykinesia, and postural instability/gait disorder. Although these symptoms have been shown to affect activities of daily living, their impact on the level of at-home physical activity (PA) in this population remains unexplored. We aimed to investigate the relationship between the four major motor symptoms of PD and at-home PA in these individuals. Methods: This retrospective cross-sectional study included 17 individuals with PD. We examined the relationship between the Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale Part 3 score and the time spent in three PA intensities (sedentary behavior, light PA [LPA], and moderate-to-vigorous PA) within the home. Pearson’s correlation coefficient was used for statistical analysis. Results: In the initial step analysis, a significant negative correlation was observed between the overall motor symptom score and the time spent in LPA inside the home (rs [95% confidence interval]: −0.72 [−0.93 to −0.25]; p < 0.01). In the second step analysis, a significant negative correlation was observed between the bradykinesia score and the time spent in LPA inside the home (rs: −0.74 [−0.92 to −0.30]; p < 0.01). Conclusions: Among the four major motor symptoms, only the severity of bradykinesia influenced the time spent in LPA inside the home. Thus, rehabilitation treatment focusing on bradykinesia may be beneficial for increasing the time spent in LPA inside the home for individuals with PD.
KW - Parkinson’s disease
KW - at-home activity
KW - bradykinesia
KW - triaxial accelerometer
UR - https://www.scopus.com/pages/publications/105017160077
UR - https://www.scopus.com/pages/publications/105017160077#tab=citedBy
U2 - 10.3390/neurolint17090139
DO - 10.3390/neurolint17090139
M3 - Article
AN - SCOPUS:105017160077
SN - 2035-8385
VL - 17
JO - Neurology International
JF - Neurology International
IS - 9
M1 - 139
ER -