Relationship Between Mortality and Cancer-Bearing Status in Patients With Chronic Kidney Disease Who Attended an Educational Program

Akihito Tanaka, Daijo Inaguma, Yu Watanabe, Minako Murata, Hibiki Shinjo, Kiyomi Koike, Yasuhiro Otsuka, Asami Takeda

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Patients with malignancy have a poorer prognosis than others do, which must be taken into consideration when treating them for chronic kidney disease (CKD). However, there are few studies investigating their prognosis. This was an observational study of 515 (394 men and 121 women) stable non-dialysis patients with CKD who attended a CKD educational program. Mean age was 68.8 ± 13.0 years. Median follow-up was 968.5 days. Mean creatinine was 3.4 ± 1.6 mg/dL. Of these, 63 had malignancy and 452 did not; 20.6% of the former and 11.9% of the latter group died by the end of the study period (P = 0.0548). Malignancy was not associated with all-cause mortality (HR: 1.3475, 95% CI: 0.7202–2.5214, P = 0.3507) but with malignancy-associated mortality (HR: 3.9477, 95% CI: 1.6348–9.5331, P = 0.0023). Renal replacement therapy was not associated with mortality. Since malignancy greatly affects the prognosis, it must be taken into consideration when treating these patients.

Original languageEnglish
Pages (from-to)49-57
Number of pages9
JournalTherapeutic Apheresis and Dialysis
Volume22
Issue number1
DOIs
Publication statusPublished - 01-02-2018

All Science Journal Classification (ASJC) codes

  • Hematology
  • Nephrology

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