Relationship between radiation pneumonitis and organizing pneumonia after radiotherapy for breast cancer

Yumi Oie, Yasunori Saito, Masanao Kato, Fumitaka Ito, Hidekazu Hattori, Hiroshi Toyama, Hidetoshi Kobayashi, Kazuhiro Katada

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Background: Radiation pneumonitis (RP) and organizing pneumonia (OP) are the two main types of lung damage that can occur after lung irradiation. The goal of this study was to evaluate the relationship between RP and OP after irradiation for breast cancer.Methods: Four hundred and twenty-eight patients who underwent radiotherapy for breast cancer were identified. The whole breast was irradiated with two tangential photon beams. Chest computed tomography (CT) scan were performed when patients showed any symptoms that were suspicious for pneumonitis.Results: Five patients (1.2%) were diagnosed with OP. All five patients showed ground glass opacities and consolidation of the border of the lesion of RP in the radiation fields. Infiltration of OP spread from the site of RP to the hilum of the ipsilateral lung. Between RP and OP, a free region space (FRS) could be detected.Conclusions: OP is closely related to RP. All OP lesions developed near the site of RP.

Original languageEnglish
Article number56
JournalRadiation Oncology
Volume8
Issue number1
DOIs
Publication statusPublished - 08-03-2013

All Science Journal Classification (ASJC) codes

  • Oncology
  • Radiology Nuclear Medicine and imaging

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