Relationship of Soluble Fas with Body Mass Index in Healthy Japanese Adults

Akiko Tamakoshi, Koji Suzuki, Yingsong Lin, Yoshinori Ito, Kiyoko Yagyu, Shogo Kikuchi, Yoshiyuki Watanabe, Yutaka Inaba, Kazuo Tajima, Kei Nakachi, Mitsuru Mori, Fumio Sakauchi, Yutaka Motohashi, Ichiro Tsuji, Yosikazu Nakamura, Hiroyasu Iso, Haruo Mikami, Michiko Kurosawa, Yoshiharu Hoshiyama, Naohito TanabeKoji Tamakoshi, Kenji Wakai, Shinkan Tokudome, Shuji Hashimoto, Shogo Kikuchi, Yasuhiko Wada, Takashi Kawamura, Yoshiyuki Watanabe, Kotaro Ozasa, Tsuneharu Miki, Chigusa Date, Kiyomi Sakata, Yoichi Kurozawa, Takesumi Yoshimura, Yoshihisa Fujino, Akira Shibata, Naoyuki Okamoto, Hideo Shio

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Recent studies have linked elevated serum sFas levels to atherosclerotic disease among patients. Confirming an association between obesity and serum sFas levels in healthy subjects would facilitate our understanding of obesity and its related disorders. We therefore analyzed serum sFas levels of 8,541 subjects selected as controls for a nested case-control study within the JACC Study. Body mass index (BMI) was calculated as the indicator of obesity based on self-reported height and weight. We found a statistically significant positive association between serum sFas levels and BMI among our apparently healthy subjects. Our result suggests that serum sFas rises to down-regulate increased apoptosis in atherogenesis processes caused by obesity.

Original languageEnglish
Pages (from-to)41-44
Number of pages4
JournalAsian Pacific Journal of Cancer Prevention
Volume10
Issue numberSUPPL.1
Publication statusPublished - 01-01-2009

Fingerprint

Body Mass Index
Obesity
Serum
Healthy Volunteers
Case-Control Studies
Atherosclerosis
Down-Regulation
Apoptosis
Weights and Measures

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Oncology
  • Public Health, Environmental and Occupational Health
  • Cancer Research

Cite this

Tamakoshi, A., Suzuki, K., Lin, Y., Ito, Y., Yagyu, K., Kikuchi, S., ... Shio, H. (2009). Relationship of Soluble Fas with Body Mass Index in Healthy Japanese Adults. Asian Pacific Journal of Cancer Prevention, 10(SUPPL.1), 41-44.
Tamakoshi, Akiko ; Suzuki, Koji ; Lin, Yingsong ; Ito, Yoshinori ; Yagyu, Kiyoko ; Kikuchi, Shogo ; Watanabe, Yoshiyuki ; Inaba, Yutaka ; Tajima, Kazuo ; Nakachi, Kei ; Mori, Mitsuru ; Sakauchi, Fumio ; Motohashi, Yutaka ; Tsuji, Ichiro ; Nakamura, Yosikazu ; Iso, Hiroyasu ; Mikami, Haruo ; Kurosawa, Michiko ; Hoshiyama, Yoshiharu ; Tanabe, Naohito ; Tamakoshi, Koji ; Wakai, Kenji ; Tokudome, Shinkan ; Hashimoto, Shuji ; Kikuchi, Shogo ; Wada, Yasuhiko ; Kawamura, Takashi ; Watanabe, Yoshiyuki ; Ozasa, Kotaro ; Miki, Tsuneharu ; Date, Chigusa ; Sakata, Kiyomi ; Kurozawa, Yoichi ; Yoshimura, Takesumi ; Fujino, Yoshihisa ; Shibata, Akira ; Okamoto, Naoyuki ; Shio, Hideo. / Relationship of Soluble Fas with Body Mass Index in Healthy Japanese Adults. In: Asian Pacific Journal of Cancer Prevention. 2009 ; Vol. 10, No. SUPPL.1. pp. 41-44.
@article{92df3b87384146dab28e43b63e05613c,
title = "Relationship of Soluble Fas with Body Mass Index in Healthy Japanese Adults",
abstract = "Recent studies have linked elevated serum sFas levels to atherosclerotic disease among patients. Confirming an association between obesity and serum sFas levels in healthy subjects would facilitate our understanding of obesity and its related disorders. We therefore analyzed serum sFas levels of 8,541 subjects selected as controls for a nested case-control study within the JACC Study. Body mass index (BMI) was calculated as the indicator of obesity based on self-reported height and weight. We found a statistically significant positive association between serum sFas levels and BMI among our apparently healthy subjects. Our result suggests that serum sFas rises to down-regulate increased apoptosis in atherogenesis processes caused by obesity.",
author = "Akiko Tamakoshi and Koji Suzuki and Yingsong Lin and Yoshinori Ito and Kiyoko Yagyu and Shogo Kikuchi and Yoshiyuki Watanabe and Yutaka Inaba and Kazuo Tajima and Kei Nakachi and Mitsuru Mori and Fumio Sakauchi and Yutaka Motohashi and Ichiro Tsuji and Yosikazu Nakamura and Hiroyasu Iso and Haruo Mikami and Michiko Kurosawa and Yoshiharu Hoshiyama and Naohito Tanabe and Koji Tamakoshi and Kenji Wakai and Shinkan Tokudome and Shuji Hashimoto and Shogo Kikuchi and Yasuhiko Wada and Takashi Kawamura and Yoshiyuki Watanabe and Kotaro Ozasa and Tsuneharu Miki and Chigusa Date and Kiyomi Sakata and Yoichi Kurozawa and Takesumi Yoshimura and Yoshihisa Fujino and Akira Shibata and Naoyuki Okamoto and Hideo Shio",
year = "2009",
month = "1",
day = "1",
language = "English",
volume = "10",
pages = "41--44",
journal = "Asian Pacific Journal of Cancer Prevention",
issn = "1513-7368",
publisher = "Asian Pacific Organization for Cancer Prevention",
number = "SUPPL.1",

}

Tamakoshi, A, Suzuki, K, Lin, Y, Ito, Y, Yagyu, K, Kikuchi, S, Watanabe, Y, Inaba, Y, Tajima, K, Nakachi, K, Mori, M, Sakauchi, F, Motohashi, Y, Tsuji, I, Nakamura, Y, Iso, H, Mikami, H, Kurosawa, M, Hoshiyama, Y, Tanabe, N, Tamakoshi, K, Wakai, K, Tokudome, S, Hashimoto, S, Kikuchi, S, Wada, Y, Kawamura, T, Watanabe, Y, Ozasa, K, Miki, T, Date, C, Sakata, K, Kurozawa, Y, Yoshimura, T, Fujino, Y, Shibata, A, Okamoto, N & Shio, H 2009, 'Relationship of Soluble Fas with Body Mass Index in Healthy Japanese Adults', Asian Pacific Journal of Cancer Prevention, vol. 10, no. SUPPL.1, pp. 41-44.

Relationship of Soluble Fas with Body Mass Index in Healthy Japanese Adults. / Tamakoshi, Akiko; Suzuki, Koji; Lin, Yingsong; Ito, Yoshinori; Yagyu, Kiyoko; Kikuchi, Shogo; Watanabe, Yoshiyuki; Inaba, Yutaka; Tajima, Kazuo; Nakachi, Kei; Mori, Mitsuru; Sakauchi, Fumio; Motohashi, Yutaka; Tsuji, Ichiro; Nakamura, Yosikazu; Iso, Hiroyasu; Mikami, Haruo; Kurosawa, Michiko; Hoshiyama, Yoshiharu; Tanabe, Naohito; Tamakoshi, Koji; Wakai, Kenji; Tokudome, Shinkan; Hashimoto, Shuji; Kikuchi, Shogo; Wada, Yasuhiko; Kawamura, Takashi; Watanabe, Yoshiyuki; Ozasa, Kotaro; Miki, Tsuneharu; Date, Chigusa; Sakata, Kiyomi; Kurozawa, Yoichi; Yoshimura, Takesumi; Fujino, Yoshihisa; Shibata, Akira; Okamoto, Naoyuki; Shio, Hideo.

In: Asian Pacific Journal of Cancer Prevention, Vol. 10, No. SUPPL.1, 01.01.2009, p. 41-44.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Relationship of Soluble Fas with Body Mass Index in Healthy Japanese Adults

AU - Tamakoshi, Akiko

AU - Suzuki, Koji

AU - Lin, Yingsong

AU - Ito, Yoshinori

AU - Yagyu, Kiyoko

AU - Kikuchi, Shogo

AU - Watanabe, Yoshiyuki

AU - Inaba, Yutaka

AU - Tajima, Kazuo

AU - Nakachi, Kei

AU - Mori, Mitsuru

AU - Sakauchi, Fumio

AU - Motohashi, Yutaka

AU - Tsuji, Ichiro

AU - Nakamura, Yosikazu

AU - Iso, Hiroyasu

AU - Mikami, Haruo

AU - Kurosawa, Michiko

AU - Hoshiyama, Yoshiharu

AU - Tanabe, Naohito

AU - Tamakoshi, Koji

AU - Wakai, Kenji

AU - Tokudome, Shinkan

AU - Hashimoto, Shuji

AU - Kikuchi, Shogo

AU - Wada, Yasuhiko

AU - Kawamura, Takashi

AU - Watanabe, Yoshiyuki

AU - Ozasa, Kotaro

AU - Miki, Tsuneharu

AU - Date, Chigusa

AU - Sakata, Kiyomi

AU - Kurozawa, Yoichi

AU - Yoshimura, Takesumi

AU - Fujino, Yoshihisa

AU - Shibata, Akira

AU - Okamoto, Naoyuki

AU - Shio, Hideo

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Recent studies have linked elevated serum sFas levels to atherosclerotic disease among patients. Confirming an association between obesity and serum sFas levels in healthy subjects would facilitate our understanding of obesity and its related disorders. We therefore analyzed serum sFas levels of 8,541 subjects selected as controls for a nested case-control study within the JACC Study. Body mass index (BMI) was calculated as the indicator of obesity based on self-reported height and weight. We found a statistically significant positive association between serum sFas levels and BMI among our apparently healthy subjects. Our result suggests that serum sFas rises to down-regulate increased apoptosis in atherogenesis processes caused by obesity.

AB - Recent studies have linked elevated serum sFas levels to atherosclerotic disease among patients. Confirming an association between obesity and serum sFas levels in healthy subjects would facilitate our understanding of obesity and its related disorders. We therefore analyzed serum sFas levels of 8,541 subjects selected as controls for a nested case-control study within the JACC Study. Body mass index (BMI) was calculated as the indicator of obesity based on self-reported height and weight. We found a statistically significant positive association between serum sFas levels and BMI among our apparently healthy subjects. Our result suggests that serum sFas rises to down-regulate increased apoptosis in atherogenesis processes caused by obesity.

UR - http://www.scopus.com/inward/record.url?scp=77957326362&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77957326362&partnerID=8YFLogxK

M3 - Article

C2 - 20553080

AN - SCOPUS:77957326362

VL - 10

SP - 41

EP - 44

JO - Asian Pacific Journal of Cancer Prevention

JF - Asian Pacific Journal of Cancer Prevention

SN - 1513-7368

IS - SUPPL.1

ER -

Tamakoshi A, Suzuki K, Lin Y, Ito Y, Yagyu K, Kikuchi S et al. Relationship of Soluble Fas with Body Mass Index in Healthy Japanese Adults. Asian Pacific Journal of Cancer Prevention. 2009 Jan 1;10(SUPPL.1):41-44.