Relative activities of pyridine nucleotides themselves to nicotinic acid as niacin nutriture were investigated using Lactobacillus plantarum ATCC 8014. This organism is generally used as a test organism for measuring the niacin contents in foods, because this organism lacks the de novo NAD biosynthetic pathway, therefore, nicotinic acid or nicotinamide is required for growth. Nicotinic acid mononucleotide and nicotinic acid adenine dinucleotide had little niacin activity, while nicotinamide mononucleotide, NAD+, and NADP+ had a little niacin activity and the relative activity of the respective compound to nicotinic acid as niacin nutriture was 1/14, 1/5, and 1/33.
All Science Journal Classification (ASJC) codes
- Analytical Chemistry
- Applied Microbiology and Biotechnology
- Molecular Biology
- Organic Chemistry