TY - JOUR
T1 - Rigid bronchoscopic intervention for endobronchial metastasis of renal cell carcinoma
AU - Tsuboi, Rie
AU - Oki, Masahide
AU - Saka, Hideo
AU - Kogure, Yoshihito
AU - Oka, Saori
AU - Nakahata, Masashi
AU - Hori, Kazumi
AU - Murakami, Yasushi
AU - Ise, Yuko
AU - Moursi Ahmed, Shimaa Nour
AU - Tao, Meimei
AU - Kitagawa, Chiyoe
N1 - Publisher Copyright:
© 2016 The Japanese Respiratory Society
PY - 2016/7
Y1 - 2016/7
N2 - Background: Renal cell carcinoma is one of the major endobronchial metastases, and it occasionally causes life-threatening airway obstruction. Rigid bronchoscopy is useful as a palliative intervention; however, its utility for metastatic renal cell carcinoma has not been elucidated. The purpose of this study was to evaluate the safety and efficacy of rigid bronchoscopic treatment for endobronchial metastasis of renal cell carcinoma. Methods: Among 550 patients who underwent rigid bronchoscopic intervention at a single center from January 2005 to June 2015, 9 with metastatic renal cell carcinoma were retrospectively reviewed. Procedures were performed with rigid and flexible bronchoscopes under general anesthesia. Results: In total, 20 procedures were performed on 9 patients who underwent stent implantation. Bleeding was observed in 12 (60%) procedures while severe hypoxia was observed in 2 (10%). The required amount of supplemental oxygen successfully decreased after all the 10 procedures (100%) in patients who previously needed it. Median survival after the first procedure was of 260 days (range, 63–913 days). Conclusions: Rigid bronchoscopic intervention for endobronchial metastasis of renal cell carcinoma is feasible with safety and effectiveness for palliation of airway obstruction, if one prepares sufficiently for massive intraoperative bleeding.
AB - Background: Renal cell carcinoma is one of the major endobronchial metastases, and it occasionally causes life-threatening airway obstruction. Rigid bronchoscopy is useful as a palliative intervention; however, its utility for metastatic renal cell carcinoma has not been elucidated. The purpose of this study was to evaluate the safety and efficacy of rigid bronchoscopic treatment for endobronchial metastasis of renal cell carcinoma. Methods: Among 550 patients who underwent rigid bronchoscopic intervention at a single center from January 2005 to June 2015, 9 with metastatic renal cell carcinoma were retrospectively reviewed. Procedures were performed with rigid and flexible bronchoscopes under general anesthesia. Results: In total, 20 procedures were performed on 9 patients who underwent stent implantation. Bleeding was observed in 12 (60%) procedures while severe hypoxia was observed in 2 (10%). The required amount of supplemental oxygen successfully decreased after all the 10 procedures (100%) in patients who previously needed it. Median survival after the first procedure was of 260 days (range, 63–913 days). Conclusions: Rigid bronchoscopic intervention for endobronchial metastasis of renal cell carcinoma is feasible with safety and effectiveness for palliation of airway obstruction, if one prepares sufficiently for massive intraoperative bleeding.
KW - Airway stenosis
KW - Airway stent
KW - Bronchoscopy
KW - Central airway obstruction
KW - Renal cell carcinoma
UR - https://www.scopus.com/pages/publications/84960157346
UR - https://www.scopus.com/inward/citedby.url?scp=84960157346&partnerID=8YFLogxK
U2 - 10.1016/j.resinv.2016.02.003
DO - 10.1016/j.resinv.2016.02.003
M3 - Article
C2 - 27424824
AN - SCOPUS:84960157346
SN - 2212-5345
VL - 54
SP - 250
EP - 254
JO - Respiratory Investigation
JF - Respiratory Investigation
IS - 4
ER -