Risk factors for age related maculopathy in a Japanese population

The Hisayama study

Miho Miyazaki, H. Nakamura, Michiaki Kubo, Y. Kiyohara, Y. Oshima, T. Ishibashi, Y. Nose

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

Aims: To examine the risk factors for age related maculopathy (ARM) in a sample Japanese population. Methods: In 1998, a cross sectional community survey was conducted among residents of Hisayama. A total of 596 men and 886 women living in Hisayama, Japan, aged 50 years or older consented to participate in the study. Each participant underwent a comprehensive examination that included an ophthalmic examination. The presence of ARM was determined by grading from fundus examination by indirect ophthalmoscopy, slit lamp examination, and colour fundus photographs. Using these cross sectional data, logistic regression analyses were performed to determine the risk factors for ARM. The following 10 possible risk factors were used: age, cataract, hypertension (history), hypertension (history or examination), diabetes, hyperlipidaemia, current smoker, alcohol intake, BMI, and WBC. Results: ARM was detected in 19.5% of men and 14.9% of women. Men were found to have a significantly higher prevalence of ARM than women. Multiple logistic regression analysis showed that age and hypertension (history or examination) were significantly associated with ARM in men, whereas only age was a significant risk factor for ARM in women. Conclusions: This study suggests that higher age and male sex are relevant risk factors for ARM in Japan. In addition, hypertension is a relevant risk factor in men.

Original languageEnglish
Pages (from-to)469-472
Number of pages4
JournalBritish Journal of Ophthalmology
Volume87
Issue number4
DOIs
Publication statusPublished - 01-04-2003
Externally publishedYes

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Macular Degeneration
Population
Hypertension
History
Japan
Logistic Models
Regression Analysis
Ophthalmoscopy
Hyperlipidemias
Cataract
Color
Cross-Sectional Studies
Alcohols

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Miyazaki, Miho ; Nakamura, H. ; Kubo, Michiaki ; Kiyohara, Y. ; Oshima, Y. ; Ishibashi, T. ; Nose, Y. / Risk factors for age related maculopathy in a Japanese population : The Hisayama study. In: British Journal of Ophthalmology. 2003 ; Vol. 87, No. 4. pp. 469-472.
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abstract = "Aims: To examine the risk factors for age related maculopathy (ARM) in a sample Japanese population. Methods: In 1998, a cross sectional community survey was conducted among residents of Hisayama. A total of 596 men and 886 women living in Hisayama, Japan, aged 50 years or older consented to participate in the study. Each participant underwent a comprehensive examination that included an ophthalmic examination. The presence of ARM was determined by grading from fundus examination by indirect ophthalmoscopy, slit lamp examination, and colour fundus photographs. Using these cross sectional data, logistic regression analyses were performed to determine the risk factors for ARM. The following 10 possible risk factors were used: age, cataract, hypertension (history), hypertension (history or examination), diabetes, hyperlipidaemia, current smoker, alcohol intake, BMI, and WBC. Results: ARM was detected in 19.5{\%} of men and 14.9{\%} of women. Men were found to have a significantly higher prevalence of ARM than women. Multiple logistic regression analysis showed that age and hypertension (history or examination) were significantly associated with ARM in men, whereas only age was a significant risk factor for ARM in women. Conclusions: This study suggests that higher age and male sex are relevant risk factors for ARM in Japan. In addition, hypertension is a relevant risk factor in men.",
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Miyazaki, M, Nakamura, H, Kubo, M, Kiyohara, Y, Oshima, Y, Ishibashi, T & Nose, Y 2003, 'Risk factors for age related maculopathy in a Japanese population: The Hisayama study', British Journal of Ophthalmology, vol. 87, no. 4, pp. 469-472. https://doi.org/10.1136/bjo.87.4.469

Risk factors for age related maculopathy in a Japanese population : The Hisayama study. / Miyazaki, Miho; Nakamura, H.; Kubo, Michiaki; Kiyohara, Y.; Oshima, Y.; Ishibashi, T.; Nose, Y.

In: British Journal of Ophthalmology, Vol. 87, No. 4, 01.04.2003, p. 469-472.

Research output: Contribution to journalArticle

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AU - Miyazaki, Miho

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AU - Kiyohara, Y.

AU - Oshima, Y.

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AU - Nose, Y.

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N2 - Aims: To examine the risk factors for age related maculopathy (ARM) in a sample Japanese population. Methods: In 1998, a cross sectional community survey was conducted among residents of Hisayama. A total of 596 men and 886 women living in Hisayama, Japan, aged 50 years or older consented to participate in the study. Each participant underwent a comprehensive examination that included an ophthalmic examination. The presence of ARM was determined by grading from fundus examination by indirect ophthalmoscopy, slit lamp examination, and colour fundus photographs. Using these cross sectional data, logistic regression analyses were performed to determine the risk factors for ARM. The following 10 possible risk factors were used: age, cataract, hypertension (history), hypertension (history or examination), diabetes, hyperlipidaemia, current smoker, alcohol intake, BMI, and WBC. Results: ARM was detected in 19.5% of men and 14.9% of women. Men were found to have a significantly higher prevalence of ARM than women. Multiple logistic regression analysis showed that age and hypertension (history or examination) were significantly associated with ARM in men, whereas only age was a significant risk factor for ARM in women. Conclusions: This study suggests that higher age and male sex are relevant risk factors for ARM in Japan. In addition, hypertension is a relevant risk factor in men.

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