TY - JOUR
T1 - Risk factors for portal vein complications in pediatric living donor liver transplantation
AU - Shibasaki, Susumu
AU - Taniguchi, Masahiko
AU - Shimamura, Tsuyoshi
AU - Suzuki, Tomomi
AU - Yamashita, Kenichiro
AU - Wakayama, Kenji
AU - Hirokata, Gentaro
AU - Ohta, Minoru
AU - Kamiyama, Toshiya
AU - Matsushita, Michiaki
AU - Furukawa, Hiroyuki
AU - Todo, Satoru
PY - 2010/7
Y1 - 2010/7
N2 - Background: Portal vein (PV) complications in pediatric living donor liver transplantation (LDLT) are often asymptomatic in the early stages after transplantation and can be serious enough to lead to graft failure. There have been few reports on risk factors for PV complications in LDLT. The aim of this study is to investigate the influence of hepatic inflow upon PV complications and to predict patients at risk for these complications. Material/method: From 1997 to 2008, 46 pediatric patients underwent LDLT at our center. Portal venous and hepatic arterial flows and PV diameter were analyzed. Results: PV complications were identified in seven patients (15.2%) and occurred at a younger age and lower weight. As a result of appropriate treatment, none of the patients suffered graft failure. Analysis of the 46 patients and 27 patients under two yr of age indentified smaller PV diameter in recipient and larger discrepancy of PV diameter as risk factors. Portal venous flow tended to be low, in contrast to hepatic arterial flow, which tended to be high. Conclusion: PV size strongly influences PV complications. Other factors such as younger age, low portal venous flow, and high hepatic arterial flow may be risk factors for PV complications.
AB - Background: Portal vein (PV) complications in pediatric living donor liver transplantation (LDLT) are often asymptomatic in the early stages after transplantation and can be serious enough to lead to graft failure. There have been few reports on risk factors for PV complications in LDLT. The aim of this study is to investigate the influence of hepatic inflow upon PV complications and to predict patients at risk for these complications. Material/method: From 1997 to 2008, 46 pediatric patients underwent LDLT at our center. Portal venous and hepatic arterial flows and PV diameter were analyzed. Results: PV complications were identified in seven patients (15.2%) and occurred at a younger age and lower weight. As a result of appropriate treatment, none of the patients suffered graft failure. Analysis of the 46 patients and 27 patients under two yr of age indentified smaller PV diameter in recipient and larger discrepancy of PV diameter as risk factors. Portal venous flow tended to be low, in contrast to hepatic arterial flow, which tended to be high. Conclusion: PV size strongly influences PV complications. Other factors such as younger age, low portal venous flow, and high hepatic arterial flow may be risk factors for PV complications.
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U2 - 10.1111/j.1399-0012.2009.01123.x
DO - 10.1111/j.1399-0012.2009.01123.x
M3 - Article
C2 - 19925458
AN - SCOPUS:77955734939
SN - 0902-0063
VL - 24
SP - 550
EP - 556
JO - Clinical Transplantation
JF - Clinical Transplantation
IS - 4
ER -