Risk factors for portal vein complications in pediatric living donor liver transplantation

Susumu Shibasaki, Masahiko Taniguchi, Tsuyoshi Shimamura, Tomomi Suzuki, Kenichiro Yamashita, Kenji Wakayama, Gentaro Hirokata, Minoru Ohta, Toshiya Kamiyama, Michiaki Matsushita, Hiroyuki Furukawa, Satoru Todo

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

Background: Portal vein (PV) complications in pediatric living donor liver transplantation (LDLT) are often asymptomatic in the early stages after transplantation and can be serious enough to lead to graft failure. There have been few reports on risk factors for PV complications in LDLT. The aim of this study is to investigate the influence of hepatic inflow upon PV complications and to predict patients at risk for these complications. Material/method: From 1997 to 2008, 46 pediatric patients underwent LDLT at our center. Portal venous and hepatic arterial flows and PV diameter were analyzed. Results: PV complications were identified in seven patients (15.2%) and occurred at a younger age and lower weight. As a result of appropriate treatment, none of the patients suffered graft failure. Analysis of the 46 patients and 27 patients under two yr of age indentified smaller PV diameter in recipient and larger discrepancy of PV diameter as risk factors. Portal venous flow tended to be low, in contrast to hepatic arterial flow, which tended to be high. Conclusion: PV size strongly influences PV complications. Other factors such as younger age, low portal venous flow, and high hepatic arterial flow may be risk factors for PV complications.

Original languageEnglish
Pages (from-to)550-556
Number of pages7
JournalClinical Transplantation
Volume24
Issue number4
DOIs
Publication statusPublished - 07-2010
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Transplantation

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