TY - JOUR
T1 - Risk factors for surgical site infection in Japanese patients with ulcerative colitis
T2 - A multicenter prospective study
AU - Araki, Toshimitsu
AU - Okita, Yoshiki
AU - Uchino, Motoi
AU - Ikeuchi, Hiroki
AU - Sasaki, Iwao
AU - Funayama, Yuji
AU - Fukushima, Kouhei
AU - Futami, Kitarou
AU - Maeda, Kiyoshi
AU - Iiai, Tsuneo
AU - Itabashi, Michio
AU - Hase, Kazuo
AU - Motoya, Satoshi
AU - Kitano, Atsuo
AU - Mizushima, Tsunekazu
AU - Maeda, Kotaro
AU - Kobayashi, Minako
AU - Mohri, Yasuhiko
AU - Kusunoki, Masato
N1 - Funding Information:
This study was supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan and by Labor Sciences Research Grants for Intractable Diseases from the Ministry of Health, Labor, and Welfare of Japan.
PY - 2014/6
Y1 - 2014/6
N2 - Purpose: A prospective, multicenter, observational study was performed to investigate the risk factors of surgical site infection (SSI) in patients with ulcerative colitis (UC). Methods: From 2009 to 2010, perioperative clinicopathological data were collected from patients who had undergone surgery for UC within the research period, for up to 6 consecutive months in 13 hospitals in Japan. The primary outcome was the development of SSI. Results: A total of 195 patients with UC who underwent colorectal surgery were enrolled. SSI was diagnosed in 38 (19.5 %) patients, in the form of incisional infection in 23 (11.8 %), organ/space infection in 16 (8.2 %), and both in 1 (0.5 %). There were no significant risk factors associated with an increased risk of development of incisional SSI. An American Society of Anesthesiologists physical status of ≥ 3 was indicated as the only significant risk factor for organ/space SSI (P = 0.02) compared with other factors, such as a neutrophil count of >100 × 102/mm3, albumin level of <3.5 g/dl, perioperative packed red blood cell transfusion, fair or poor colonic cleanliness, and therapeutic use of antibiotics. Conclusion: Poor general physical status was the significant independent risk factor for organ/space SSI in patients with UC in Japan.
AB - Purpose: A prospective, multicenter, observational study was performed to investigate the risk factors of surgical site infection (SSI) in patients with ulcerative colitis (UC). Methods: From 2009 to 2010, perioperative clinicopathological data were collected from patients who had undergone surgery for UC within the research period, for up to 6 consecutive months in 13 hospitals in Japan. The primary outcome was the development of SSI. Results: A total of 195 patients with UC who underwent colorectal surgery were enrolled. SSI was diagnosed in 38 (19.5 %) patients, in the form of incisional infection in 23 (11.8 %), organ/space infection in 16 (8.2 %), and both in 1 (0.5 %). There were no significant risk factors associated with an increased risk of development of incisional SSI. An American Society of Anesthesiologists physical status of ≥ 3 was indicated as the only significant risk factor for organ/space SSI (P = 0.02) compared with other factors, such as a neutrophil count of >100 × 102/mm3, albumin level of <3.5 g/dl, perioperative packed red blood cell transfusion, fair or poor colonic cleanliness, and therapeutic use of antibiotics. Conclusion: Poor general physical status was the significant independent risk factor for organ/space SSI in patients with UC in Japan.
KW - Complication
KW - Multicenter surveillance
KW - Surgical site infection
KW - Ulcerative colitis
UR - https://www.scopus.com/pages/publications/84901289921
UR - https://www.scopus.com/pages/publications/84901289921#tab=citedBy
U2 - 10.1007/s00595-013-0809-9
DO - 10.1007/s00595-013-0809-9
M3 - Article
C2 - 24337501
AN - SCOPUS:84901289921
SN - 0941-1291
VL - 44
SP - 1072
EP - 1078
JO - Surgery Today
JF - Surgery Today
IS - 6
ER -