Robot-assisted partial nephrectomy with minimum follow-up of 5 years: A multi-center prospective study in Japan

Junya Furukawa, Nobuyuki Hinata, Jun Teisima, Atsushi Takenaka, Ryoichi Shiroki, Yasuyuki Kobayashi, Hiro omi Kanayama, Kazunori Hattori, Shigeo Horie, Keiichi Tozawa, Masashi Kato, Chikara Ohyama, Tomonori Habuchi, Naoki Kawamorita, Masatoshi Eto, Masato Fujisawa

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8 Citations (Scopus)


Objectives: Robot-assisted partial nephrectomy is widely performed for small renal masses, achieving excellent perioperative and intermediate oncological outcomes. However, long-term oncological, functional, and quality of life outcomes after robot-assisted partial nephrectomy remain unclear. In this study, we aimed to evaluate quality of life at 1 year and oncological and functional outcomes of robot-assisted partial nephrectomy after a minimum follow-up of 5 years. Methods: Personal, perioperative, postoperative, functional, oncological, and quality of life data were evaluated. The EQ-5D-5L tool, which incorporates health profiles and a EuroQol Visual Analog Scale, was used to assess quality of life preoperatively and 365 days postoperatively. Regarding oncological and functional outcomes, overall survival, recurrence-free survival, and changes in estimated glomerular filtration rate were calculated. Results: There were few changes in levels between the two time points for all EQ-5D dimensions. The mean change in EQ-5D-5L was 0.020 (95% confidence interval 0.006–0.033, P = 0.006), and in EuroQol Visual Analog Scale score 4.60 (95% confidence interval 2.17–7.02, P = 0.0003). Overall and recurrence-free survival 5 years after robot-assisted partial nephrectomy were 97.9% and 92.8%, respectively. After an early postoperative decrease, the estimated glomerular filtration rate remained stable over time. Conclusions: Robot-assisted partial nephrectomy in patients with a T1 renal tumor is safe, feasible, and effective from the perspective of quality of life and survival, even after 5 years. When making treatment decisions, perioperative and quality of life outcomes should be considered together with long-term oncological outcomes.

Original languageEnglish
JournalInternational Journal of Urology
Publication statusPublished - 09-2022

All Science Journal Classification (ASJC) codes

  • Urology


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