Role of CRMP-2 in neuronal polarization

Nariko Arimura, Takeshi Oshimura, Kozo Kaibuchi

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The neuron is one of the most dramatic examples of a polarized cell forming two distinctive types of neurites, an axon and dendrites. Neuronal polarization begins in a symmetric cell with the elongation of one of the immature neurites as an axon. Polarization enables the two types of neurites to perform different functions: sending and receiving electrical signals in a vectorial fashion. Although researchers are accumulating a catalog of structural, molecular, and functional differences between axons and dendrites, the mechanisms involved in the establishment of neuronal polarity are not well understood.

Original languageEnglish
Title of host publicationIntracellular Mechanisms for Neuritogenesis
PublisherSpringer US
Pages239-252
Number of pages14
ISBN (Print)038733128X, 9780387331287
DOIs
Publication statusPublished - 2007
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

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