Abstract
Rotavirus, a member of the family Reoviridae, was identified as the leading etiological agent of severe gastroenteritis in infants and young children in 1973. The rotavirus genome is composed of 11 gene segments of double-stranded (ds)RNA. During the last 40 years, a large amount of basic research on rotavirus structure, genome, antigen, replication, pathogenesis, epidemiology, immune responses, and evolution has been accumulated. This article reviews the fundamental aspects of rotavirology including recent important achievements in research.
| Original language | English |
|---|---|
| Pages (from-to) | 179-190 |
| Number of pages | 12 |
| Journal | Uirusu |
| Volume | 64 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 01-01-2014 |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
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Rotaviruses. / Komoto, Satoshi; Taniguchi, Koki.
In: Uirusu, Vol. 64, No. 2, 01.01.2014, p. 179-190.Research output: Contribution to journal › Review article
TY - JOUR
T1 - Rotaviruses
AU - Komoto, Satoshi
AU - Taniguchi, Koki
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Rotavirus, a member of the family Reoviridae, was identified as the leading etiological agent of severe gastroenteritis in infants and young children in 1973. The rotavirus genome is composed of 11 gene segments of double-stranded (ds)RNA. During the last 40 years, a large amount of basic research on rotavirus structure, genome, antigen, replication, pathogenesis, epidemiology, immune responses, and evolution has been accumulated. This article reviews the fundamental aspects of rotavirology including recent important achievements in research.
AB - Rotavirus, a member of the family Reoviridae, was identified as the leading etiological agent of severe gastroenteritis in infants and young children in 1973. The rotavirus genome is composed of 11 gene segments of double-stranded (ds)RNA. During the last 40 years, a large amount of basic research on rotavirus structure, genome, antigen, replication, pathogenesis, epidemiology, immune responses, and evolution has been accumulated. This article reviews the fundamental aspects of rotavirology including recent important achievements in research.
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UR - http://www.scopus.com/inward/citedby.url?scp=84981487672&partnerID=8YFLogxK
U2 - 10.2222/jsv.64.179
DO - 10.2222/jsv.64.179
M3 - Review article
VL - 64
SP - 179
EP - 190
JO - Uirusu. Journal of virology
JF - Uirusu. Journal of virology
SN - 0042-6857
IS - 2
ER -