Rotaviruses

Satoshi Komoto, Koki Taniguchi

Research output: Contribution to journalReview articlepeer-review

8 Citations (Scopus)

Abstract

Rotavirus, a member of the family Reoviridae, was identified as the leading etiological agent of severe gastroenteritis in infants and young children in 1973. The rotavirus genome is composed of 11 gene segments of double-stranded (ds)RNA. During the last 40 years, a large amount of basic research on rotavirus structure, genome, antigen, replication, pathogenesis, epidemiology, immune responses, and evolution has been accumulated. This article reviews the fundamental aspects of rotavirology including recent important achievements in research.

Original languageEnglish
Pages (from-to)179-190
Number of pages12
JournalUirusu
Volume64
Issue number2
DOIs
Publication statusPublished - 2014

All Science Journal Classification (ASJC) codes

  • General Medicine

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