Safety study of skin care cosmetics for sensitive skin in patients with a history of contact dermatitis and/or atopic dermatitis

Miki Tanioka, Yoshiki Miyachi, Setsuya Aiba, Katsuko Kikuchi, Osamu Ishikawa, Yayoi Nagai, Tadashi Terui, Hidenao Shimizu, Masatoshi Ito, Hiromi Kantoh, Kayoko Matsunaga, Akiko Yagami, Ichiro Katayama, Shigeki Inui, Masamitsu Ishii, Hiromi Kobayashi, Atsuko Kato, Masutaka Furue, Noriko Fukiwake, Syuhei Imayama & 1 others Yumiko Suzuki

Research output: Contribution to journalArticle

Abstract

We carried out a four-week study in patients with a history of contact dermatitis and/or atopic dermatitis in order to assess the safety of new sensitive-skin cosmetics containing hyaluronic acid. We found adverse skin reactions in 9.6% of the subjects who used the lotion (enriched type), in 6.7% of the subjects who used the lotion (light type), in 8.2% of the subjects who used the emulsion, and in 6.5% of the subjects who used the cream. These adverse skin reactions were slight or moderate, and there was no severe reaction. All subjects presented with dryness of the face at week 0 on clinical examination. More than 85% of the subjects exhibited improvement of facial skin dryness at 4 weeks. The satisfaction index for skin condition, obtained by using a visual analog scale, showed a notable improvement after the study. The results indicate that these skin care cosmetics are safe and useful for patients with contact dermatitis and/or atopic dermatitis.

Original languageEnglish
Pages (from-to)263-273
Number of pages11
JournalSkin Research
Volume7
Issue number2
Publication statusPublished - 01-04-2008

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Skin Care
Contact Dermatitis
Atopic Dermatitis
Cosmetics
Safety
Skin
Hyaluronic Acid
Emulsions
Visual Analog Scale
Light

All Science Journal Classification (ASJC) codes

  • Dermatology
  • Infectious Diseases

Cite this

Tanioka, M., Miyachi, Y., Aiba, S., Kikuchi, K., Ishikawa, O., Nagai, Y., ... Suzuki, Y. (2008). Safety study of skin care cosmetics for sensitive skin in patients with a history of contact dermatitis and/or atopic dermatitis. Skin Research, 7(2), 263-273.
Tanioka, Miki ; Miyachi, Yoshiki ; Aiba, Setsuya ; Kikuchi, Katsuko ; Ishikawa, Osamu ; Nagai, Yayoi ; Terui, Tadashi ; Shimizu, Hidenao ; Ito, Masatoshi ; Kantoh, Hiromi ; Matsunaga, Kayoko ; Yagami, Akiko ; Katayama, Ichiro ; Inui, Shigeki ; Ishii, Masamitsu ; Kobayashi, Hiromi ; Kato, Atsuko ; Furue, Masutaka ; Fukiwake, Noriko ; Imayama, Syuhei ; Suzuki, Yumiko. / Safety study of skin care cosmetics for sensitive skin in patients with a history of contact dermatitis and/or atopic dermatitis. In: Skin Research. 2008 ; Vol. 7, No. 2. pp. 263-273.
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abstract = "We carried out a four-week study in patients with a history of contact dermatitis and/or atopic dermatitis in order to assess the safety of new sensitive-skin cosmetics containing hyaluronic acid. We found adverse skin reactions in 9.6{\%} of the subjects who used the lotion (enriched type), in 6.7{\%} of the subjects who used the lotion (light type), in 8.2{\%} of the subjects who used the emulsion, and in 6.5{\%} of the subjects who used the cream. These adverse skin reactions were slight or moderate, and there was no severe reaction. All subjects presented with dryness of the face at week 0 on clinical examination. More than 85{\%} of the subjects exhibited improvement of facial skin dryness at 4 weeks. The satisfaction index for skin condition, obtained by using a visual analog scale, showed a notable improvement after the study. The results indicate that these skin care cosmetics are safe and useful for patients with contact dermatitis and/or atopic dermatitis.",
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Tanioka, M, Miyachi, Y, Aiba, S, Kikuchi, K, Ishikawa, O, Nagai, Y, Terui, T, Shimizu, H, Ito, M, Kantoh, H, Matsunaga, K, Yagami, A, Katayama, I, Inui, S, Ishii, M, Kobayashi, H, Kato, A, Furue, M, Fukiwake, N, Imayama, S & Suzuki, Y 2008, 'Safety study of skin care cosmetics for sensitive skin in patients with a history of contact dermatitis and/or atopic dermatitis', Skin Research, vol. 7, no. 2, pp. 263-273.

Safety study of skin care cosmetics for sensitive skin in patients with a history of contact dermatitis and/or atopic dermatitis. / Tanioka, Miki; Miyachi, Yoshiki; Aiba, Setsuya; Kikuchi, Katsuko; Ishikawa, Osamu; Nagai, Yayoi; Terui, Tadashi; Shimizu, Hidenao; Ito, Masatoshi; Kantoh, Hiromi; Matsunaga, Kayoko; Yagami, Akiko; Katayama, Ichiro; Inui, Shigeki; Ishii, Masamitsu; Kobayashi, Hiromi; Kato, Atsuko; Furue, Masutaka; Fukiwake, Noriko; Imayama, Syuhei; Suzuki, Yumiko.

In: Skin Research, Vol. 7, No. 2, 01.04.2008, p. 263-273.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Safety study of skin care cosmetics for sensitive skin in patients with a history of contact dermatitis and/or atopic dermatitis

AU - Tanioka, Miki

AU - Miyachi, Yoshiki

AU - Aiba, Setsuya

AU - Kikuchi, Katsuko

AU - Ishikawa, Osamu

AU - Nagai, Yayoi

AU - Terui, Tadashi

AU - Shimizu, Hidenao

AU - Ito, Masatoshi

AU - Kantoh, Hiromi

AU - Matsunaga, Kayoko

AU - Yagami, Akiko

AU - Katayama, Ichiro

AU - Inui, Shigeki

AU - Ishii, Masamitsu

AU - Kobayashi, Hiromi

AU - Kato, Atsuko

AU - Furue, Masutaka

AU - Fukiwake, Noriko

AU - Imayama, Syuhei

AU - Suzuki, Yumiko

PY - 2008/4/1

Y1 - 2008/4/1

N2 - We carried out a four-week study in patients with a history of contact dermatitis and/or atopic dermatitis in order to assess the safety of new sensitive-skin cosmetics containing hyaluronic acid. We found adverse skin reactions in 9.6% of the subjects who used the lotion (enriched type), in 6.7% of the subjects who used the lotion (light type), in 8.2% of the subjects who used the emulsion, and in 6.5% of the subjects who used the cream. These adverse skin reactions were slight or moderate, and there was no severe reaction. All subjects presented with dryness of the face at week 0 on clinical examination. More than 85% of the subjects exhibited improvement of facial skin dryness at 4 weeks. The satisfaction index for skin condition, obtained by using a visual analog scale, showed a notable improvement after the study. The results indicate that these skin care cosmetics are safe and useful for patients with contact dermatitis and/or atopic dermatitis.

AB - We carried out a four-week study in patients with a history of contact dermatitis and/or atopic dermatitis in order to assess the safety of new sensitive-skin cosmetics containing hyaluronic acid. We found adverse skin reactions in 9.6% of the subjects who used the lotion (enriched type), in 6.7% of the subjects who used the lotion (light type), in 8.2% of the subjects who used the emulsion, and in 6.5% of the subjects who used the cream. These adverse skin reactions were slight or moderate, and there was no severe reaction. All subjects presented with dryness of the face at week 0 on clinical examination. More than 85% of the subjects exhibited improvement of facial skin dryness at 4 weeks. The satisfaction index for skin condition, obtained by using a visual analog scale, showed a notable improvement after the study. The results indicate that these skin care cosmetics are safe and useful for patients with contact dermatitis and/or atopic dermatitis.

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Tanioka M, Miyachi Y, Aiba S, Kikuchi K, Ishikawa O, Nagai Y et al. Safety study of skin care cosmetics for sensitive skin in patients with a history of contact dermatitis and/or atopic dermatitis. Skin Research. 2008 Apr 1;7(2):263-273.