Sars-cov-2 infection among medical institution faculty and healthcare workers in tokyo, japan

Tomoyasu Nishimura, Yoshifumi Uwamino, Shunsuke Uno, Shoko Kashimura, Toshikimi Shiraki, Toshinobu Kurafuji, Maasa Morita, Masayo Noguchi, Tatsuhiko Azegami, Nobuko Yamada-Goto, Ayano Murai-Takeda, Hirokazu Yokoyama, Kazuyo Kuwabara, Suzuka Kato, Minako Matsumoto, Aya Hirata, Miho Iida, Sei Harada, Tamami Ishizaka, Kana MisawaMitsuru Murata, Hideyuki Saya, Masayuki Amagai, Yuko Kitagawa, Tsutomu Takeuchi, Masaaki Mori, Toru Takebayashi, Naoki Hasegawa

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Objective To consider effective measures against severe acute respiratory syndrome coronavirus 2 (SARSCoV- 2) infection in medical institutions, this study estimated the SARS-CoV-2 infection rate among healthcare workers (HCWs) in Tokyo, Japan, and determined the specific findings for mild coronavirus disease 2019 (COVID-19) cases. Methods This study analyzed the results of serologic tests to detect immunoglobulin G antibodies against SARS-CoV-2 and evaluated the demographic and clinical characteristics of the faculty and HCWs at a Tokyo medical institution in August 2020. The demographic and clinical characteristics of participants with antibody-positive results were compared to those of participants with antibody-negative results. Materials This study recruited 2,341 faculty and HCWs at a Tokyo medical institution, 21 of whom had a COVID-19 history. Results Of the 2,320 participants without a COVID-19 history, 20 (0.862%) had positive serologic test results. A fever and dysgeusia or dysosmia occurred with greater frequency among the participants with positive test results than in those with negative results [odds ratio (OR), 5.475; 95% confidence interval (CI), 1.960-15.293 and OR, 24.158; 95% CI, 2.693-216.720, respectively]. No significant difference was observed in the positivity rate between HCWs providing medical care for COVID-19 patients using adequate protection and other HCWs (OR, 2.514; 95% CI, 0.959-6.588). Conclusion To reduce the risk of COVID-19 spread in medical institutions, faculty and HCWs should follow standard and necessary transmission-based precautions, and those with a fever and dysgeusia or dysosmia should excuse themselves from work as soon as possible.

Original languageEnglish
Pages (from-to)2569-2575
Number of pages7
JournalInternal Medicine
Issue number16
Publication statusPublished - 2021
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Internal Medicine


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