Septic shock with emphysematous cholecystitis and disseminated infection caused by hypervirulent Klebsiella pneumoniae capsular genotype K2-ST65 in a Japanese man with diabetes mellitus: A case report

Yoshifumi Kubota; Haruhiko Ishioka; Sohei Harada; Masahiro Suzuki; Junji Shiotsuka; Alan Kawarai Lefor; Masamitsu Sanui

doi:10.1016/j.jiac.2020.09.017

Septic shock with emphysematous cholecystitis and disseminated infection caused by hypervirulent Klebsiella pneumoniae capsular genotype K2-ST65 in a Japanese man with diabetes mellitus: A case report

Yoshifumi Kubota
, Haruhiko Ishioka
, Sohei Harada
, Masahiro Suzuki
, Junji Shiotsuka
, Alan Kawarai Lefor
, Masamitsu Sanui

Microbiology

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Hypervirulent Klebsiella pneumoniae capsular genotypes K1 and K2 are common pathogens responsible for community-acquired liver abscesses and invasive infections especially in East Asia. We report a Japanese man with diabetes mellitus who rapidly developed emphysematous cholecystitis and fulminant disseminated infection with life-threatening multiple organ-system failure due to K. pneumoniae K2 strains belonging to sequence type 65. In East Asia, clinicians should be aware of fulminant infections caused by hypervirulent K2 strains in patients with community-acquired K. pneumoniae infections. Further epidemiological studies are warranted to elucidate the clinical features associated with the virulence K. pneumoniae K2 strains.

Original language	English
Pages (from-to)	350-353
Number of pages	4
Journal	Journal of Infection and Chemotherapy
Volume	27
Issue number	2
DOIs	https://doi.org/10.1016/j.jiac.2020.09.017
Publication status	Published - 02-2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Infectious Diseases
Pharmacology (medical)

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10.1016/j.jiac.2020.09.017

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Kubota, Y., Ishioka, H., Harada, S., Suzuki, M., Shiotsuka, J., Lefor, A. K., & Sanui, M. (2021). Septic shock with emphysematous cholecystitis and disseminated infection caused by hypervirulent Klebsiella pneumoniae capsular genotype K2-ST65 in a Japanese man with diabetes mellitus: A case report. Journal of Infection and Chemotherapy, 27(2), 350-353. https://doi.org/10.1016/j.jiac.2020.09.017

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title = "Septic shock with emphysematous cholecystitis and disseminated infection caused by hypervirulent Klebsiella pneumoniae capsular genotype K2-ST65 in a Japanese man with diabetes mellitus: A case report",

abstract = "Hypervirulent Klebsiella pneumoniae capsular genotypes K1 and K2 are common pathogens responsible for community-acquired liver abscesses and invasive infections especially in East Asia. We report a Japanese man with diabetes mellitus who rapidly developed emphysematous cholecystitis and fulminant disseminated infection with life-threatening multiple organ-system failure due to K. pneumoniae K2 strains belonging to sequence type 65. In East Asia, clinicians should be aware of fulminant infections caused by hypervirulent K2 strains in patients with community-acquired K. pneumoniae infections. Further epidemiological studies are warranted to elucidate the clinical features associated with the virulence K. pneumoniae K2 strains.",

keywords = "Capsular genotypes K2, Critical care medicine, East Asia, Emphysematous cholecystitis, Hypervirulent Klebsiella pneumoniae, Septic shock",

author = "Yoshifumi Kubota and Haruhiko Ishioka and Sohei Harada and Masahiro Suzuki and Junji Shiotsuka and Lefor, \{Alan Kawarai\} and Masamitsu Sanui",

note = "Publisher Copyright: {\textcopyright} 2020 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases",

year = "2021",

month = feb,

doi = "10.1016/j.jiac.2020.09.017",

language = "English",

volume = "27",

pages = "350--353",

journal = "Journal of Infection and Chemotherapy",

issn = "1341-321X",

publisher = "Elsevier B.V.",

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}

Kubota, Y, Ishioka, H, Harada, S, Suzuki, M, Shiotsuka, J, Lefor, AK & Sanui, M 2021, 'Septic shock with emphysematous cholecystitis and disseminated infection caused by hypervirulent Klebsiella pneumoniae capsular genotype K2-ST65 in a Japanese man with diabetes mellitus: A case report', Journal of Infection and Chemotherapy, vol. 27, no. 2, pp. 350-353. https://doi.org/10.1016/j.jiac.2020.09.017

Septic shock with emphysematous cholecystitis and disseminated infection caused by hypervirulent Klebsiella pneumoniae capsular genotype K2-ST65 in a Japanese man with diabetes mellitus: A case report. / Kubota, Yoshifumi; Ishioka, Haruhiko; Harada, Sohei et al.
In: Journal of Infection and Chemotherapy, Vol. 27, No. 2, 02.2021, p. 350-353.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Septic shock with emphysematous cholecystitis and disseminated infection caused by hypervirulent Klebsiella pneumoniae capsular genotype K2-ST65 in a Japanese man with diabetes mellitus

T2 - A case report

AU - Kubota, Yoshifumi

AU - Ishioka, Haruhiko

AU - Harada, Sohei

AU - Suzuki, Masahiro

AU - Shiotsuka, Junji

AU - Lefor, Alan Kawarai

AU - Sanui, Masamitsu

PY - 2021/2

Y1 - 2021/2

N2 - Hypervirulent Klebsiella pneumoniae capsular genotypes K1 and K2 are common pathogens responsible for community-acquired liver abscesses and invasive infections especially in East Asia. We report a Japanese man with diabetes mellitus who rapidly developed emphysematous cholecystitis and fulminant disseminated infection with life-threatening multiple organ-system failure due to K. pneumoniae K2 strains belonging to sequence type 65. In East Asia, clinicians should be aware of fulminant infections caused by hypervirulent K2 strains in patients with community-acquired K. pneumoniae infections. Further epidemiological studies are warranted to elucidate the clinical features associated with the virulence K. pneumoniae K2 strains.

AB - Hypervirulent Klebsiella pneumoniae capsular genotypes K1 and K2 are common pathogens responsible for community-acquired liver abscesses and invasive infections especially in East Asia. We report a Japanese man with diabetes mellitus who rapidly developed emphysematous cholecystitis and fulminant disseminated infection with life-threatening multiple organ-system failure due to K. pneumoniae K2 strains belonging to sequence type 65. In East Asia, clinicians should be aware of fulminant infections caused by hypervirulent K2 strains in patients with community-acquired K. pneumoniae infections. Further epidemiological studies are warranted to elucidate the clinical features associated with the virulence K. pneumoniae K2 strains.

KW - Capsular genotypes K2

KW - Critical care medicine

KW - East Asia

KW - Emphysematous cholecystitis

KW - Hypervirulent Klebsiella pneumoniae

KW - Septic shock

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UR - https://www.scopus.com/pages/publications/85091914707#tab=citedBy

U2 - 10.1016/j.jiac.2020.09.017

DO - 10.1016/j.jiac.2020.09.017

M3 - Article

C2 - 33008737

AN - SCOPUS:85091914707

SN - 1341-321X

VL - 27

SP - 350

EP - 353

JO - Journal of Infection and Chemotherapy

JF - Journal of Infection and Chemotherapy

IS - 2

ER -

Septic shock with emphysematous cholecystitis and disseminated infection caused by hypervirulent Klebsiella pneumoniae capsular genotype K2-ST65 in a Japanese man with diabetes mellitus: A case report

Abstract

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