Sequence specificity of the human autonomously replicating sequence binding protein.

S. Izuta; M. Suzuki; K. Kojima; S. Yoshida

Sequence specificity of the human autonomously replicating sequence binding protein.

S. Izuta, M. Suzuki, K. Kojima, S. Yoshida

Research output: Contribution to journal › Article › peer-review

Abstract

We have previously found that the protein which bound to the essential region of human autonomously replicating sequences (ARS) could be the c-myc proto-oncogene product. Here we examined the binding specificity of human ARS binding protein purified from Burkitt's lymphoma Raji cells. Among several oligodeoxynucleotides, this protein bound to the fragments containing the sequence of 5'-CAPyCTCTNA-3'. Competition analysis revealed that the ARS binding protein could recognize not only the nucleotide sequences but also the high ordered structure.

Original language	English
Pages (from-to)	21-22
Number of pages	2
Journal	Nucleic acids symposium series
Issue number	21
Publication status	Published - 1989
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Medicine

Cite this

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abstract = "We have previously found that the protein which bound to the essential region of human autonomously replicating sequences (ARS) could be the c-myc proto-oncogene product. Here we examined the binding specificity of human ARS binding protein purified from Burkitt's lymphoma Raji cells. Among several oligodeoxynucleotides, this protein bound to the fragments containing the sequence of 5'-CAPyCTCTNA-3'. Competition analysis revealed that the ARS binding protein could recognize not only the nucleotide sequences but also the high ordered structure.",

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AU - Suzuki, M.

AU - Kojima, K.

AU - Yoshida, S.

PY - 1989

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N2 - We have previously found that the protein which bound to the essential region of human autonomously replicating sequences (ARS) could be the c-myc proto-oncogene product. Here we examined the binding specificity of human ARS binding protein purified from Burkitt's lymphoma Raji cells. Among several oligodeoxynucleotides, this protein bound to the fragments containing the sequence of 5'-CAPyCTCTNA-3'. Competition analysis revealed that the ARS binding protein could recognize not only the nucleotide sequences but also the high ordered structure.

AB - We have previously found that the protein which bound to the essential region of human autonomously replicating sequences (ARS) could be the c-myc proto-oncogene product. Here we examined the binding specificity of human ARS binding protein purified from Burkitt's lymphoma Raji cells. Among several oligodeoxynucleotides, this protein bound to the fragments containing the sequence of 5'-CAPyCTCTNA-3'. Competition analysis revealed that the ARS binding protein could recognize not only the nucleotide sequences but also the high ordered structure.

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ER -

Sequence specificity of the human autonomously replicating sequence binding protein.

Abstract

All Science Journal Classification (ASJC) codes

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