Sequence specificity of the human autonomously replicating sequence binding protein.

S. Izuta, Motoshi Suzuki, K. Kojima, S. Yoshida

Research output: Contribution to journalArticle

Abstract

We have previously found that the protein which bound to the essential region of human autonomously replicating sequences (ARS) could be the c-myc proto-oncogene product. Here we examined the binding specificity of human ARS binding protein purified from Burkitt's lymphoma Raji cells. Among several oligodeoxynucleotides, this protein bound to the fragments containing the sequence of 5'-CAPyCTCTNA-3'. Competition analysis revealed that the ARS binding protein could recognize not only the nucleotide sequences but also the high ordered structure.

Original languageEnglish
Pages (from-to)21-22
Number of pages2
JournalNucleic acids symposium series
Issue number21
Publication statusPublished - 01-01-1989

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Carrier Proteins
Proto-Oncogene Proteins c-myc
Burkitt Lymphoma
Oligodeoxyribonucleotides
Proteins

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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Sequence specificity of the human autonomously replicating sequence binding protein. / Izuta, S.; Suzuki, Motoshi; Kojima, K.; Yoshida, S.

In: Nucleic acids symposium series, No. 21, 01.01.1989, p. 21-22.

Research output: Contribution to journalArticle

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