Abstract
Collagenase-like(CL) peptidase activity in serum, which was measured using a newly synthesized substrate, (succinyl-Gly-Pro-Leu-Gly-Pro)-4-methylcoumaryl-7-amide, was significantly lower in patients with advanced rheumatoid arthritis or with systemic lupus erythematosus than that in normal controls. Decrease of the serum enzyme activity was more pronounced in systemic lupus erythematosus. No significant change in serum CL-peptidase activity was found in other connective tissue diseases such as mixed connective tissue disease and Sjogren's syndrome.
| Original language | English |
|---|---|
| Pages (from-to) | 75-79 |
| Number of pages | 5 |
| Journal | Clinica Chimica Acta |
| Volume | 146 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 28-02-1985 |
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All Science Journal Classification (ASJC) codes
- Biochemistry
- Clinical Biochemistry
- Biochemistry, medical
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Serum collagenase-like peptidase activity in rheumatoid arthritis and systemic lupus erythematosus. / Kimi, Iwase Okadaa; Toshiharu, Nagatsua; Keisuke, Fujita; Katsutaka, Torikai; Tatsuo, Hamamoto; Tsunehiro, Shibata; Maeno, Yoshimasa; Shumpei, Sakakibara.
In: Clinica Chimica Acta, Vol. 146, No. 1, 28.02.1985, p. 75-79.Research output: Contribution to journal › Article
TY - JOUR
T1 - Serum collagenase-like peptidase activity in rheumatoid arthritis and systemic lupus erythematosus
AU - Kimi, Iwase Okadaa
AU - Toshiharu, Nagatsua
AU - Keisuke, Fujita
AU - Katsutaka, Torikai
AU - Tatsuo, Hamamoto
AU - Tsunehiro, Shibata
AU - Maeno, Yoshimasa
AU - Shumpei, Sakakibara
PY - 1985/2/28
Y1 - 1985/2/28
N2 - Collagenase-like(CL) peptidase activity in serum, which was measured using a newly synthesized substrate, (succinyl-Gly-Pro-Leu-Gly-Pro)-4-methylcoumaryl-7-amide, was significantly lower in patients with advanced rheumatoid arthritis or with systemic lupus erythematosus than that in normal controls. Decrease of the serum enzyme activity was more pronounced in systemic lupus erythematosus. No significant change in serum CL-peptidase activity was found in other connective tissue diseases such as mixed connective tissue disease and Sjogren's syndrome.
AB - Collagenase-like(CL) peptidase activity in serum, which was measured using a newly synthesized substrate, (succinyl-Gly-Pro-Leu-Gly-Pro)-4-methylcoumaryl-7-amide, was significantly lower in patients with advanced rheumatoid arthritis or with systemic lupus erythematosus than that in normal controls. Decrease of the serum enzyme activity was more pronounced in systemic lupus erythematosus. No significant change in serum CL-peptidase activity was found in other connective tissue diseases such as mixed connective tissue disease and Sjogren's syndrome.
UR - http://www.scopus.com/inward/record.url?scp=0021880773&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021880773&partnerID=8YFLogxK
U2 - 10.1016/0009-8981(85)90125-1
DO - 10.1016/0009-8981(85)90125-1
M3 - Article
VL - 146
SP - 75
EP - 79
JO - Clinica Chimica Acta
JF - Clinica Chimica Acta
SN - 0009-8981
IS - 1
ER -