Abstract
We measured the serum concentration of lidocaine after transversus abdominis plane (TAP) block with 40 ml of 1% lidocaine in 12 patients under general anesthesia, using a fluorescence polarization immunoassay. The peak mean serum concentration of lidocaine occurred 30 min after the block (3.6 ± 0.7 μg·ml-1). The highest concentration of lidocaine (5.5μg·ml-1) was recorded 15 min after the block. These results indicate that a TAP block can potentially cause systemic toxicity of a local anesthetic. The analgesic effect of the TAP block may partially depend on the rise in serum concentration of the local anesthetic.
Original language | English |
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Pages (from-to) | 298-300 |
Number of pages | 3 |
Journal | Journal of Anesthesia |
Volume | 23 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2009 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Anesthesiology and Pain Medicine