Serum concentrations of carotenoids, retinol, and α-tocopherol in healthy persons determined by high-performance liquid chromatography

Yoshinori Ito, Junichi Ochiai, Ryuichiro Sasaki, Sadao Suzuki, Yasuhiro Kusuhara, Youichi Morimitsu, Motohiko Otani, Kunio Aoki

Research output: Contribution to journalArticlepeer-review

115 Citations (Scopus)

Abstract

Serum concentrations of α-carotene (AC), β-carotene (BC), lycopene (LY), β-cryptoxanthin (CR), zeaxanthin (including lutein, ZX), canthaxanthin (CX), retinol (RE), and α-tocopherol (TO) in healthy persons (618 males and 1196 females) aged 7-86 years were determined by HPLC. Serum concentrations of BC among persons aged 20-49 years were higher with increasing age in females, but not in males. Serum CR concentrations decreased with age ranging from 7 to 39 years, while ZX concentrations rose in the age group of 20 to 59 years for both sexes. In contrast, serum RE concentrations and ratios of RE BC and RE CR, especially in males aged 20-49, were higher with age. Serum TO values in both sexes rose with age and were similar.

Original languageEnglish
Pages (from-to)131-144
Number of pages14
JournalClinica Chimica Acta
Volume194
Issue number2-3
DOIs
Publication statusPublished - 24-12-1990
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Clinical Biochemistry
  • Biochemistry, medical

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