Sialographic study in patients with and without antibodies to Sjogren's syndrome A (Ro)

K. Miyachi, M. Naito, Y. Maeno, S. Suzuki, T. Hamamoto, M. Sugiura, M. Kasahara, K. Torikai, H. Umeda

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15 Citations (Scopus)


Antibodies to Sjogren's syndrome A (SS-A) (Ro) antigen were detected in 13 of 16 (81%) patients with sicca alone and 18 of 34 (54%) patients with systemic lupus erythematosus (SLE). Antibodies to Sjogren's syndrome B (SS-B) (La, Ha) antigen were detected in 7 of 16 (44%) patients with sicca alone. These percentages were statistically higher than those in other types of connective tissue diseases. There were no direct correlations between titers of antibodies to SS-A (Ro) and severity of sialographic abnormalities in 35 patients with Sjogren's syndrome (SS). However comparison of a total of 20 sialograms obtained from patients with antibodies to SS-A (Ro) showed more advanced changes than in a total of 36 sialograms from patients without antibodies to SS-A (Ro) in systemic lupus erythematosus, mixed connective tissue disease, progressive systemic sclerosis and rheumatoid arthritis. These results suggested that antibody to SS-A (Ro) may be a good indicator of subclinical SS.

Original languageEnglish
Pages (from-to)387-394
Number of pages8
JournalJournal of Rheumatology
Issue number3
Publication statusPublished - 1983
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Rheumatology
  • Immunology


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