Specific cell-mediated immunity in fish

T. Nakanishi, K. Aoyagi, C. Xia, J・m Dijkstra, M. Ototake

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

This review describes the fish immune system, focusing on specific cell- mediated immunity. Specific in vivo cell-mediated immune responses have been shown by allograft rejection, graft-versus-host reaction (GVHR) and delayed hypersensitivity reaction (DTH). Recent in vitro studies also showed specific cell-mediated cytotoxicity against allogeneic target cells. These in vivo and in vitro experiments strongly suggest the presence of cytotoxic T cells in fishes. Also described are current studies on shark and trout MHC class I polymorphism and function that demonstrate strong similarities between fish and mammals.

Original languageEnglish
Pages (from-to)101-109
Number of pages9
JournalVeterinary Immunology and Immunopathology
Volume72
Issue number1-2
DOIs
Publication statusPublished - 15-12-1999

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Cellular Immunity
cell-mediated immunity
Fishes
graft versus host reactions
fish
Sharks
graft rejection
delayed hypersensitivity
Trout
Delayed Hypersensitivity
Graft Rejection
sharks
polymorphism
in vitro studies
trout
Allografts
immune system
cytotoxicity
Mammals
Immune System

All Science Journal Classification (ASJC) codes

  • Immunology
  • veterinary(all)

Cite this

Nakanishi, T. ; Aoyagi, K. ; Xia, C. ; Dijkstra, J・m ; Ototake, M. / Specific cell-mediated immunity in fish. In: Veterinary Immunology and Immunopathology. 1999 ; Vol. 72, No. 1-2. pp. 101-109.
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Specific cell-mediated immunity in fish. / Nakanishi, T.; Aoyagi, K.; Xia, C.; Dijkstra, J・m; Ototake, M.

In: Veterinary Immunology and Immunopathology, Vol. 72, No. 1-2, 15.12.1999, p. 101-109.

Research output: Contribution to journalArticle

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