Spinal cord injury or spinal anesthesia eliminates seizures in myelin-deficient rats

J. Rosenbluth, M. Hasegawa

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The generalized tonic seizures that occur in myelin-deficient rats can be eliminated temporarily by spinal cord injury or spinal anesthesia. These observations imply that the seizures in this mutant can be triggered by activity in the spinal cord. The results are consistent with an earlier proposal that axons in myelin-deficient CNS fiber tracts can interact to produce abnormal excitation.

Original languageEnglish
Pages (from-to)68-72
Number of pages5
JournalNeuroscience Letters
Volume84
Issue number1
DOIs
Publication statusPublished - 11-01-1988
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

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