Study profile on baseline survey of Daiko Study in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study).

Emi Morita, Nobuyuki Hamajima, Asahi Hishida, Kyoko Aoyama, Rieko Okada, Sayo Kawai, Koutaro Tomita, Sayaka Kuriki, Takashi Tamura, Mariko Naito, Takaaki Kondo, Jun Ueyama, Akiko Kimata, Kanami Yamamoto, Yoko Hori, Junko Hoshinos, Ritsuko Hamamotos, Sanae Tsukamoto, Joji Onishi, Shoichi HagikuraHisao Naito, Satoshi Hibi, Yoshinori Ito, Kenji Wakai

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The Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study) is a long-term cohort study to investigate the interactions among genotypes, lifestyles, and lifestyle-related diseases, especially cancer. This article reports the outline of the baseline survey of the Daiko Study, one site of the J-MICC Study. That survey was conducted between June 9, 2008 and May 31, 2010 at the Daiko Medical Center of Nagoya University in Nagoya, Japan. Subjects were registered residents of Nagoya City aged 35 to 69 years who had not participated in other J-MICC sites. Recruitment was mainly announced through leaflets distributed in mailboxes citywide, personal communications, and regional information, such as posters in public or commercial facilities. Participants provided blood plasma, serum, buffy coat, urine, and data on health check-ups. They also completed a self-reported questionnaire on lifestyle, disease history, family history, and for women, reproductive history. As of the end of September 2010, 4 out of 5172 registered participants had withdrawn from the study, leaving data from 5168 participants (1467 males and 3701 females) available for analysis. Mean age +/- standard deviation (SD) was 52.5 +/- 10.3 years. Current smokers accounted for 24.1% (n=354) of males and 6.9% (n=256) of females. Current drinkers included 74.9% (n=1099) of males and 45.9% (n=1699) of females. Lifestyle data and specimens were successfully collected to examine any associations among disease biomarkers, lifestyles, and genotypes.

Original languageEnglish
Pages (from-to)187-195
Number of pages9
JournalNagoya journal of medical science
Issue number3-4
Publication statusPublished - 08-2011

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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