Subsegmental resection preserves regional pulmonary function: A focus on thoracoscopy

Hiroaki Kuroda, Shozo Sakata, Yusuke Takahashi, Takeo Nakada, Yuko Oya, Yusuke Sugita, Noriaki Sakakura, Hiroakazu Matushita, Yukinori Sakao

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Background: The aim of this study was to evaluate regional postoperative preserved pulmonary function (PPPF) and three-dimensional (3D) volumetric changes according to the number of resected subsegments and investigate the factors that most affected pre-/post PPPF. Methods: Patients who underwent thoracoscopic lobectomy (n = 73), and segmentectomy (n = 87) were eligible for inclusion in the study. They were classified according to the number of resected subsegments which ranged from 1 to 10. The percentage of pre-/postoperative forced expiratory volume in 1 s (FEV1) was used for comparison. Furthermore, lung volumetric changes were calculated using 3D computed tomography (CT) volumetry. Results: The percentage of pre-/postoperative EFV1 between 4 and 5–7 and between 5–7 and 10 were significant (p = 0.03 and p < 0.01, respectively), but not between 1–2 to 4 (p = 0.99). The difference between volumetric changes in the left lower lobe of patients with a number of resected subsegments was significant (p < 0.01). On univariate and multivariate analyses, chronic inflammation was significant for decrease in recovery percentages. When the PPPF was compared among resected subsegments, it gradually decreased with an increase in the number of patients without a postoperative procrastination of inflammation (p < 0.01). Conclusions: Segmentectomy is feasible and useful for PPPF. Even a relatively large-volume resection procedure where 5–7 subsegments are resected can preserve pulmonary function. Chronic inflammation was statistically identified as a risk factor for postoperative preserved pulmonary function. Key points:.

Original languageEnglish
Pages (from-to)1033-1040
Number of pages8
JournalThoracic Cancer
Volume12
Issue number7
DOIs
Publication statusPublished - 04-2021
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Oncology
  • Pulmonary and Respiratory Medicine

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