Successful living donor liver transplantation for fulminant hepatic failure that manifested immediately after cesarean delivery

Yoshimasa Horikoshi, Hiroaki Itoh, Suguru Kikuchi, Toshiyuki Uchida, Kazunao Suzuki, Kazuhiro Sugihara, Naohiro Kanayama, Akira Mori, Shinji Uemoto

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A 31-year-old pregnant woman was diagnosed as having acute hepatitis of unknown etiology and conservatively treated. An emergency cesarean delivery was performed 5 days later at 33 weeks and 3 days of gestation because of a gradual deterioration in liver function. Two days after the cesarean delivery, she lost consciousness in the evening (Glasgow coma scale [GCS] = 9) because of hepatic encephalopathy and was diagnosed as having fulminant hepatic failure (FHF). Five days after the cesarean delivery, the patient (blood type B) underwent a successful left lobe with caudate lobe (S1+2+3+4) liver transplantation from her father (blood type AB), an ABO-incompatible donor. At 1 year follow-up, she and her baby are in good medical condition. The drastic deterioration in hepatic function, despite intensive plasmapheresis and continuous hemodiafiltration, during the early postpartum period suggested a possible causative association between the termination of pregnancy and progression of FHF from acute hepatitis of unknown etiology.

Original languageEnglish
Pages (from-to)174-176
Number of pages3
JournalASAIO Journal
Volume58
Issue number2
DOIs
Publication statusPublished - 03-2012

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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